| Percutaneous valve replacement in a young adult for radiation-induced aortic stenosis. | |
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MedLine Citation:
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PMID: 22450861 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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A 46-year-old woman known with relapsing Hodgkin's lymphoma diagnosed at age 5, treated with repeated cycles of radiotherapy and chemotherapy, presented with severe symptomatic radiation-induced aortic stenosis. She also had other late sequelae of radiotherapy including thyroid cancer, mediastinal fribrosis and left pulmonary fibrosis with severe restrictive lung disease and a newly diagnosed renal carcinoma. Due to the prohibitively high surgical risk and need for urgent treatment, she underwent successful transcatheter aortic valve replacement with transfemoral implantation of a 23 mm Edwards SAPIEN-XT prosthesis, which was performed without valvuloplasty of the noncalcified fibrotic valve. The final result was excellent with reduction of the transaortic gradient and no residual aortic regurgitation. |
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Authors:
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Azeem Latib; Matteo Montorfano; Filippo Figini; Francesco Maisano; Alaide Chieffo; Stefano Benussi; Raimondo Bellanca; Chiara Gerli; Pietro Spagnolo; Ottavio Alfieri; Antonio Colombo |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-3-23 |
Journal Detail:
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Title: Journal of cardiovascular medicine (Hagerstown, Md.) Volume: - ISSN: 1558-2035 ISO Abbreviation: - Publication Date: 2012 Mar |
Date Detail:
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Created Date: 2012-3-27 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101259752 Medline TA: J Cardiovasc Med (Hagerstown) Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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aInterventional Cardiology Unit, San Raffaele Scientific Institute bInterventional Cardiology Unit, EMO-GVM Centro Cuore Columbus cDepartment of Cardiac Surgery, San Raffaele Scientific Institute dDepartment of Cardiac Anesthesia, San Raffaele Scientific Institute eCentre for Cardiovascular Prevention, San Raffaele Scientific Institute, Milan, Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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