Document Detail

Percutaneous transluminal venoplasty after venous pressure measurement in patients with hepatic venous outflow obstruction after living donor liver transplantation.
MedLine Citation:
PMID:  20799017     Owner:  NLM     Status:  MEDLINE    
PURPOSE: The aim of this study was to evaluate retrospectively the outcome of percutaneous transluminal venoplasty (PTV) after venous pressure measurement in patients with hepatic venous outflow obstruction following living donor liver transplantation (LDLT).
MATERIALS AND METHODS: We studied 24 consecutive patients suspected of having hepatic venous outflow obstruction after LDLT. Pressure gradients were measured proximal and distal to the lesion, and gradient values >3 mmHg were considered hemodynamically significant. We evaluated the technical success, complications, outcome of venoplasty and recurrence, and the patency rate.
RESULTS: In all, 11 female patients manifested a pressure gradient >3 mmHg across the anastomotic site; they underwent subsequent PVT. The initial balloon venoplasty procedure was technically successful in 10 of the 11 patients (91%), and the pressure gradient was reduced from 5.8 to 1.1 mmHg (P < 0.01). Clinical improvement was observed in 9 of these 10 patients; one patient failed to improve and underwent retransplantation. Recurrent obstruction occurred in four patients; they underwent PTV with (n = 2) or without (n = 2) stent placement. There were no major procedural complications.
CONCLUSION: PTV following venous pressure measurement is an effective and safe treatment for venous outflow obstruction in patients subjected to LDLT. In patients with recurrent obstruction, re-venoplasty is recommended.
Osamu Ikeda; Yoshitaka Tamura; Yutaka Nakasone; Yasuyuki Yamashita; Hideaki Okajima; Katsuhiro Asonuma; Yukihiro Inomata
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Publication Detail:
Type:  Journal Article     Date:  2010-08-27
Journal Detail:
Title:  Japanese journal of radiology     Volume:  28     ISSN:  1867-108X     ISO Abbreviation:  Jpn J Radiol     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-08-27     Completed Date:  2011-01-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101490689     Medline TA:  Jpn J Radiol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  520-6     Citation Subset:  IM    
Department of Diagnostic Radiology, Kumamoto University Graduate School of Medical and Pharmaceutical Sciences, Kumamoto, Japan.
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MeSH Terms
Balloon Dilation / methods*
Budd-Chiari Syndrome / etiology*,  radiography,  therapy*
Child, Preschool
Liver Transplantation / methods*
Living Donors
Middle Aged
Retrospective Studies
Treatment Outcome
Vascular Patency
Venous Pressure

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