Document Detail

Percutaneous transluminal ultrasonic angioplasty: preliminary clinical report of ultrasound plaque ablation in totally occluded peripheral arteries.
MedLine Citation:
PMID:  1840288     Owner:  NLM     Status:  MEDLINE    
Peripheral arterial obstructive disease has been treated with ultrasound ablation. Thirty two patients (pts), mean age 67 +/- 10 years underwent angiosonoplasty, with a prototype ultrasonic system, due to severe claudication (31%), rest pain (44%), rest pain and ulceration (25%). Angiosonoplasty was successful in 26/32 (81%) stenoses, (1/2 iliac, 9/2 femorals, 11/12 popliteal, 5/6 tibial). Angiography before and after angiosonoplasty confirmed that the lesions were successfully opened, (81%, p less than 0.05). A mean of 3 +/- 2 passes were required to adequately remove sufficient plaque. Balloon angioplasty was used in combination with angiosonoplasty in 11/32 (34%) occluded vessels. Complications included groin hematoma in 4 pts (12%) and vascular spasm in two patients (6%). Within 24 hours, 27/32 (94%) pts were discharged clinically improved. Reocclusion occurred in 4 pts (12%) immediately after the procedure. Ankle brachial indices significantly increased from 0.52 +/- 0.10 before to 0.70 +/- 0.12 after (p less than 0.05). In conclusion, the use of ultrasound energy to ablate atherosclerotic plaque would appear safe, and has shown no restenosis and a low incidence of complications over a six month period.
C Monteverde-Grether; M Valez y Tello de Meneses; G Nava-López; R Jauregui; J Borges; A Abundes; M López-Cuéllar; M Armilla
Related Documents :
1376828 - Midas: hypertension and atherosclerosis. a trial of the effects of antihypertensive dru...
17391218 - Mechanism of luminal gain with plaque excision in atherosclerotic coronary and peripher...
11348048 - Abundance of plaque microvessels is associated with constrictive remodeling in angiopla...
9328798 - Ultrasonographic assessment of regional differences in atherosclerotic lesions in patie...
2248178 - Clinical evaluation of high-frequency (ultrasonic) mechanical débridement in the surgi...
22954568 - Treatment of coronary aneurysms with covered stents: a review with illustrated case.
Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Archivos de investigación médica     Volume:  22     ISSN:  0066-6769     ISO Abbreviation:  Arch Invest Med (Mex)     Publication Date:    1991 Apr-Jun
Date Detail:
Created Date:  1992-07-30     Completed Date:  1992-07-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0262036     Medline TA:  Arch Invest Med (Mex)     Country:  MEXICO    
Other Details:
Languages:  eng     Pagination:  171-9     Citation Subset:  IM    
Coronary Care Unit, Hospital of Cardiology Luis Méndez, Centro Médico Nacional, Inst. Mexicano del Seguro Social, D.F.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Angioplasty, Balloon / instrumentation,  methods*
Arterial Occlusive Diseases / therapy*
Clinical Protocols
Combined Modality Therapy
Follow-Up Studies
Hematoma / etiology
Middle Aged
Peripheral Vascular Diseases / therapy*
Ultrasonic Therapy* / adverse effects,  instrumentation

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Renal excretory function, atrial natriuretic peptide (ANP) and plasma renin activity (PRA) during lo...
Next Document:  Preparative-scale enzyme-catalyzed peptide synthesis using solubilizing N-terminal protecting groups...