Document Detail


Percutaneous transluminal angioplasty of the aorta. Light and electron microscopic observations in normal and atherosclerotic rabbits.
MedLine Citation:
PMID:  6231654     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Histological changes which developed after percutaneous transluminal angioplasty in normal and atherosclerotic rabbit aortas were correlated with balloon size and inflation time. In normal rabbits, progressive changes were observed in the intima and media with increasing balloon size and inflation time. The atherosclerotic aortas exhibited unpredictable fragility, with limited correlation between histological changes, balloon size, and inflation time, attributable mainly to the distribution and thickness of plaques. In atherosclerotic vessels, the mechanism of angioplasty consisted of plaque dehiscence and fracture, followed by overstretching of the plaque-free wall segments. No plaque compression was observed.
Authors:
C L Zollikofer; J Chain; E Salomonowitz; W Runge; W F Bruehlmann; W R Castaneda-Zuniga; K Amplatz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Radiology     Volume:  151     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1984 May 
Date Detail:
Created Date:  1984-05-11     Completed Date:  1984-05-11     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  355-63     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Angioplasty, Balloon*
Animals
Aorta / pathology*,  ultrastructure
Aortic Diseases / pathology,  therapy*
Arteriosclerosis / pathology,  therapy*
Dilatation
Endothelium / pathology
Muscle, Smooth, Vascular / pathology
Rabbits

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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