Document Detail


Percutaneous transhepatic cholangiodrainage under real-time MRI guidance: Initial experience in an animal model.
MedLine Citation:
PMID:  21592872     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: To assess percutaneous transhepatic cholangiodrainage (PTCD) under real-time MRI-guidance and compare it to procedures performed under fluoroscopy. METHODS: We developed an in vitro model for MRI-guided and conventional PTCD, using an animal organ set including liver and bile ducts placed in an MRI-compatible box and tested it in a 1.0-Tesla open MRI-scanner. Prototype 18G needles and guide wires, standard guide wires, dilatation bougies, and drainages were used (MRI-compatible). MRI-visualization was by means of a bFFE real-time sequence using a surface coil (Flex-L). Outcome measurements were success rates and time needed for bile duct puncture using real-time MRI-guidance versus conventional radiologic methods in the model. Cannulation and drainage placement were also analysed. RESULTS: Fifty MRI-guided experiments were performed, leading to rapid (mean: 43s, range: 15-72s) and successful puncture and cannulation in 96% of procedures. Median drainage placement time was 321.5s (range: 241-411s). In 35 control experiments under fluoroscopy, puncture success was 69%, whereas times were significantly longer (mean 273s, range 45-631s). CONCLUSIONS: Initial in vitro experience shows that PTCD can be successfully and rapidly performed under real-time MRI-guidance and demonstrates improved performance compared to the conventional radiologic approach.
Authors:
Ioannis S Papanikolaou; Ivo R van der Voort; Jens Rump; Christian J Seebauer; Sascha S Chopra; Florian Wichlas; René Schilling; Thula Walter; Maria G Papas; Bertram Wiedenmann; Ulf K Teichgräber; Thomas Rösch
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-5-16
Journal Detail:
Title:  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver     Volume:  -     ISSN:  1878-3562     ISO Abbreviation:  -     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-5-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100958385     Medline TA:  Dig Liver Dis     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
Affiliation:
Central Interdisciplinary Endoscopy Unit, Charité University Hospitals Berlin, Campus Virchow Hospital, Berlin, Germany; Research Group for Engineering Instruments for the open MRI, Charité University Hospitals Berlin, Berlin, Campus Charité Mitte, Berlin, Germany.
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