Document Detail


Percutaneous thrombin injection for treatment of iatrogenic femoral artery pseudoaneurysms: a case for caution.
MedLine Citation:
PMID:  18388079     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The case of a patient who developed a femoral artery pseudoaneurysm following cardiac catheterization is described. After 2 failed attempts of ultrasound-guided compression repair, the patient underwent percutaneous thrombin injection with, beside of complete closure of the pseudoaneurysm, a severe limb ischemia due to distal thrombin migration with consecutive clot formation finally resulting in thigh amputation of the affected leg. Indications, advantages, and disadvantages of various options for the treatment of iatrogenic femoral artery pseudoaneurysms (vascular surgery, ultrasound-guided compression, percutaneous thrombin injection, and other nonsurgical treatment modalities), as well as risk factors for distal migration of liquid thrombin after percutaneous injection, are discussed in this report.
Authors:
Marc-Alexander Ohlow; Maria-Anna Secknus; Hubertus von Korn; Reginald Weiss; Bernward Lauer
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-04-02
Journal Detail:
Title:  Angiology     Volume:  59     ISSN:  1940-1574     ISO Abbreviation:  Angiology     Publication Date:    2008 Jun-Jul
Date Detail:
Created Date:  2008-06-11     Completed Date:  2008-07-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  372-5     Citation Subset:  IM    
Affiliation:
Klinik für Kardiologie, Zentralklinik, Bad Berka, Germany. m.ohlow.kar@zentralklinik-bad-berka.de
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MeSH Terms
Descriptor/Qualifier:
Aged
Amputation
Aneurysm, False / drug therapy*,  etiology,  ultrasonography
Femoral Artery* / radiography,  ultrasonography
Heart Catheterization / adverse effects*
Hemostatics / administration & dosage,  adverse effects*
Humans
Iatrogenic Disease*
Injections, Intra-Arterial
Ischemia / chemically induced*,  radiography,  surgery
Leg / blood supply*
Male
Patient Selection
Risk Assessment
Severity of Illness Index
Thrombin / administration & dosage,  adverse effects*
Chemical
Reg. No./Substance:
0/Hemostatics; EC 3.4.21.5/Thrombin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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