| Percutaneous and surgical treatment of mitral valve regurgitation. | |
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MedLine Citation:
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PMID: 22211148 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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BACKGROUND: Mitral valve regurgitation is the second most common clinically relevant valvular heart disease in adults, with an incidence of about 2% to 3% per year. Surgical mitral valve repair is the treatment of choice. Recent years have seen major advances in minimally invasive mitral valve surgery. Several new catheter-based techniques are now being clinically evaluated, including percutaneous endovascular mitral valve repair with a mitral clip. METHOD: This review is based on a selective review of the literature and on the authors' clinical experience. RESULTS: Minimally invasive and reconstructive techniques for mitral valve surgery have come into more common use in recent years. In Germany, more than 50% of all mitral valve defects are now treated with a valve-preserving repair procedure. At the same time, percutaneous techniques have been developed that enable reduction of mitral regurgitation in the cardiac catheterization laboratory, without surgery. The implantation of a mitral clip is the sole currently approved technique of this type. In a recently published, randomized comparative clinical trial (EVEREST II), it was found to be safer, but less effective, than surgery. CONCLUSION: Mitral valve surgery remains the treatment of choice for severe mitral regurgitation. For patients at high risk from surgery, and particularly those with severe heart failure, the implantation of a mitral clip is a safe and feasible treatment option. |
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Authors:
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Joerg Seeburger; Hugo A Katus; Sven T Pleger; Ulrike Krumsdorf; Friedrich-Wilhelm Mohr; Raffi Bekeredjian |
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Publication Detail:
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Type: Journal Article Date: 2011-12-02 |
Journal Detail:
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Title: Deutsches Ärzteblatt international Volume: 108 ISSN: 1866-0452 ISO Abbreviation: Dtsch Arztebl Int Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2012-01-02 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101475967 Medline TA: Dtsch Arztebl Int Country: Germany |
Other Details:
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Languages: eng Pagination: 816-21 Citation Subset: IM |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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