Document Detail

Percutaneous and surgical treatment of mitral valve regurgitation.
MedLine Citation:
PMID:  22211148     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Mitral valve regurgitation is the second most common clinically relevant valvular heart disease in adults, with an incidence of about 2% to 3% per year. Surgical mitral valve repair is the treatment of choice. Recent years have seen major advances in minimally invasive mitral valve surgery. Several new catheter-based techniques are now being clinically evaluated, including percutaneous endovascular mitral valve repair with a mitral clip.
METHOD: This review is based on a selective review of the literature and on the authors' clinical experience.
RESULTS: Minimally invasive and reconstructive techniques for mitral valve surgery have come into more common use in recent years. In Germany, more than 50% of all mitral valve defects are now treated with a valve-preserving repair procedure. At the same time, percutaneous techniques have been developed that enable reduction of mitral regurgitation in the cardiac catheterization laboratory, without surgery. The implantation of a mitral clip is the sole currently approved technique of this type. In a recently published, randomized comparative clinical trial (EVEREST II), it was found to be safer, but less effective, than surgery.
CONCLUSION: Mitral valve surgery remains the treatment of choice for severe mitral regurgitation. For patients at high risk from surgery, and particularly those with severe heart failure, the implantation of a mitral clip is a safe and feasible treatment option.
Joerg Seeburger; Hugo A Katus; Sven T Pleger; Ulrike Krumsdorf; Friedrich-Wilhelm Mohr; Raffi Bekeredjian
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Publication Detail:
Type:  Journal Article; Review     Date:  2011-12-02
Journal Detail:
Title:  Deutsches Ärzteblatt international     Volume:  108     ISSN:  1866-0452     ISO Abbreviation:  Dtsch Arztebl Int     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2012-01-02     Completed Date:  2012-04-17     Revised Date:  2013-06-26    
Medline Journal Info:
Nlm Unique ID:  101475967     Medline TA:  Dtsch Arztebl Int     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  816-21     Citation Subset:  IM    
Abteilung für Herzchirurgie, Herzzentrum Universität Leipzig.
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MeSH Terms
Heart Valve Prosthesis*
Heart Valve Prosthesis Implantation / methods*
Mitral Valve Insufficiency / surgery*
Surgical Procedures, Minimally Invasive / instrumentation*,  methods
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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