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Percutaneous nephrolithotomy: short and long term effects on health related quality of life.
MedLine Citation:
PMID:  24708396     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Background and Purpose: Percutaneous nephrolithotomy (PCNL) is the treatment of choice for large and complex kidney stones, having increased its safety and effectiveness over the last years. Nonetheless, there is little known about its impact on quality of life (QoL). This study aimed at evaluating the effects of PCNL on patients' QoL in the short and long term. Patients and Methods: We prospectively studied 40 consecutive cases who underwent PCNL. QoL was measured using the SF-36 questionnaire, 2 weeks prior to surgery and then in the third postoperative month and a year after. Changes in QoL were assessed under statistical and clinical relevance criteria. Results: PCNL has rendered 70% of the cases completely stone free with a 35% complication rate (33% Clavien I+II). The baseline scores of all SF-36 domains were worse than the referral population. Three months after PCNL, bodily pain was the only dimension whose change was relevant for patients (effect size (ES)=0.71, minimal clinically important difference (MCID)=0.56). A year after, this favorable effect of PCNL on body pain is still present, being also beneficial on both role physical (ES=0.58, MCID=0.52) and the physical component summary (PCS) (ES=0.56, MCID=0.43). Social function was also close to reaching clinical relevance a year after the procedure (ES=0.66, MCID=0.72). Conclusion: Kidney stone disease considerably affects the patients' quality of life. PCNL not only has good outcomes rendering the kidney stone free without major complications, but produces an immediate body pain relief. This is perceived as relevant by the patients even a year after the procedure, when some other physical aspects of QoL also get better, helping patients to restore their social activities.
Authors:
Daniel Adolfo Pérez-Fentes; Francisco Gude; Benito Blanco; Camilo García Freire
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-4-7
Journal Detail:
Title:  Journal of endourology / Endourological Society     Volume:  -     ISSN:  1557-900X     ISO Abbreviation:  J. Endourol.     Publication Date:  2014 Apr 
Date Detail:
Created Date:  2014-4-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8807503     Medline TA:  J Endourol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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