Document Detail

Percutaneous mitral valvuloplasty with severe pulmonary artery hypertension.
MedLine Citation:
PMID:  8342512     Owner:  NLM     Status:  MEDLINE    
The aim of this study was to assess the initial and midterm outcome of patients with severe pulmonary hypertension undergoing percutaneous mitral valvuloplasty (PMV). Accordingly, the baseline characteristics, immediate results and follow-up of 64 consecutive patients with severe pulmonary artery hypertension (systolic pulmonary artery pressure > or = 60 mm Hg on cardiac catheterization) (group I) were analyzed and compared with those of 194 consecutive patients with lower pulmonary pressures (group II). Patients in group I were more symptomatic (New York Heart Association functional class > or = III, 72 vs 40%, p < 0.001) and had higher echocardiographic scores (8.6 +/- 2 vs 7.4 +/- 1, p < 0.05). Before PMV, mitral gradient was higher (17 +/- 6 vs 13 +/- 5 mm Hg, p < 0.025) and mitral valve area smaller (0.79 +/- 0.2 vs 0.96 +/- 0.2 cm2, p < 0.005) in group I patients, who also had higher pulmonary vascular resistances (469 +/- 299 vs 157 +/- 125 dynes s-1 cm-5, p < 0.005). On multivariate analysis patients in group I were more symptomatic, had smaller mitral valve areas and higher mitral gradients. PMV success (area gain > 50% without complications) was similar (89 vs 87%) in both groups. After PMV final mitral gradient (5 +/- 2 vs 4 +/- 2 mm Hg) and area (1.82 +/- 0.5 vs 1.87 +/- 0.5 cm2) were similar in both groups.(ABSTRACT TRUNCATED AT 250 WORDS)
F Alfonso; C Macaya; R Hernandez; C Bañuelos; A Iñiguez; J Goicolea; A Fernandez-Ortiz; J Zamorano; P Zarco
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  72     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1993 Aug 
Date Detail:
Created Date:  1993-08-31     Completed Date:  1993-08-31     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  325-30     Citation Subset:  AIM; IM    
Cardiopulmonary Department, Hospital Universitario San Carlos, Madrid, Spain.
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MeSH Terms
Analysis of Variance
Balloon Dilatation* / statistics & numerical data
Chi-Square Distribution
Follow-Up Studies
Hypertension, Pulmonary / epidemiology,  etiology,  therapy*
Middle Aged
Mitral Valve*
Mitral Valve Stenosis / complications,  epidemiology,  therapy*
Pulmonary Wedge Pressure
Regression Analysis
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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