Document Detail

Percutaneous left ventricular assist devices for high-risk percutaneous coronary intervention.
MedLine Citation:
PMID:  20828347     Owner:  NLM     Status:  MEDLINE    
Although coronary artery bypass grafting remains an important therapeutic option for patients with complex coronary artery disease, percutaneous coronary intervention strategies have become an established alternative. Nevertheless, treatment options for surgery-ineligible patients with complex coronary artery disease used to be limited, especially in patients with a reduced left ventricular function. Those patients are at high risk of profound hypotension and mortality, which may be adequately prevented by prophylactic placement of a percutaneous mechanical assist device. Although many devices have been developed and randomized evidence is still pending, the Impella LP2.5 device (Abiomed-Impella CardioSystems GmbH, Aachen, Germany) seems to be promising as it is easily applicable, carries a low complication rate and provides adequate circulatory support.
Annemarie E Engström; Jan J Piek; José P S Henriques
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Expert review of cardiovascular therapy     Volume:  8     ISSN:  1744-8344     ISO Abbreviation:  Expert Rev Cardiovasc Ther     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-10     Completed Date:  2010-12-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101182328     Medline TA:  Expert Rev Cardiovasc Ther     Country:  England    
Other Details:
Languages:  eng     Pagination:  1247-55     Citation Subset:  IM    
Department of Cardiology, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
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MeSH Terms
Acute Coronary Syndrome / radiography,  therapy*
Angioplasty, Balloon, Coronary*
Coronary Angiography
Heart-Assist Devices*
Randomized Controlled Trials as Topic
Risk Factors
Ventricular Dysfunction, Left / radiography,  therapy*

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