Document Detail

Percutaneous laryngeal collagen augmentation for treatment of parkinsonian hypophonia.
MedLine Citation:
PMID:  12087333     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Our goal was to determine whether percutaneous laryngeal collagen augmentation improves hypophonia in parkinsonian patients. STUDY DESIGN AND SETTING: A retrospective review of 18 patients was performed. Patients and/or caretakers were called on the telephone and asked about their response to the procedure, if any. Videostroboscopic examinations for all patients were reviewed. RESULTS: Of 18 patients, 11 (61%) reported improvement in their hypophonia for a period of at least 2 months. Five of 7 patients without improvement were relatively aphonic both before and after the procedure. Five of 7 patients without improvement had severe dysphagia, which in 3 necessitated gastrostomy tube placement. Four of 7 patients without improvement were not ambulatory at the time of the procedure. CONCLUSIONS: Percutaneous laryngeal collagen augmentation is an effective treatment for parkinsonian hypophonia in a majority of patients. Patients with advanced neurologic disease with aphonia, difficulty with speech initiation, dysphagia, or ambulatory difficulty are less likely to respond to this procedure and should be so informed.
Soo H Kim; James J Kearney; Joseph P Atkins
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Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery     Volume:  126     ISSN:  0194-5998     ISO Abbreviation:  Otolaryngol Head Neck Surg     Publication Date:  2002 Jun 
Date Detail:
Created Date:  2002-06-27     Completed Date:  2002-08-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8508176     Medline TA:  Otolaryngol Head Neck Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  653-6     Citation Subset:  IM    
Department of Otolaryngology-Head and Neck Surgery, Hospital of the University of Pennsylvania, Philadelphia 19104, USA.
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MeSH Terms
Collagen / therapeutic use*
Follow-Up Studies
Glottis / drug effects*,  physiopathology
Injections, Intralesional
Middle Aged
Parkinson Disease / complications*,  diagnosis
Patient Satisfaction
Retrospective Studies
Severity of Illness Index
Treatment Outcome
Voice Disorders / drug therapy*,  etiology
Reg. No./Substance:

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