Document Detail

Percutaneous intervention of unprotected left main coronary artery.
MedLine Citation:
PMID:  12800408     Owner:  NLM     Status:  MEDLINE    
Successful percutaneous intervention of unprotected left main coronary artery (LMCA) in lieu of surgical revascularization represents the next wave of challenges that the field of interventional cardiology will try to overcome. Significant LMCA stenosis, commonly secondary to atherosclerosis, is seen in about 4-10% of cases presenting to the cardiac catheterization laboratory. Currently, the vast majority of these patients undergo surgical revascularization unless there are prohibitive reasons for surgical revascularization. Several challenges of percutaneous revascularization have been overcome with stents, intravascular brachytherapy, and other technical improvements. Yet, several remaining limitations of percutaneous intervention, such as in-stent restenosis, have to be improved further before randomized clinical trials of surgical and percutaneous revascularization of unprotected LMCA disease can be contemplated to establish a new standard of care.
H Mehrdad Sadeghi; William W O'Neill; Cindy L Grines
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of interventional cardiology     Volume:  16     ISSN:  0896-4327     ISO Abbreviation:  J Interv Cardiol     Publication Date:  2003 Jun 
Date Detail:
Created Date:  2003-06-12     Completed Date:  2003-07-11     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8907826     Medline TA:  J Interv Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  281-8     Citation Subset:  IM    
Department of Medicine, Division of Cardiology, William Beaumont Hospital, Royal Oak, Michigan, USA.
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MeSH Terms
Arteries / surgery*
Coronary Angiography
Coronary Stenosis / diagnosis,  epidemiology,  etiology,  surgery
Coronary Vessels / surgery*
Myocardial Revascularization* / trends
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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