| Percutaneous fetal sclerotherapy for congenital cystic adenomatoid malformation of the lung. | |
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MedLine Citation:
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PMID: 18753764 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: Congenital cystic adenomatoid malformation (CCAM) is a rare lesion of the developing fetal lung consisting of increased cell proliferation in the bronchial structures with lack of differentiation of the alveoli. Pregnancies may be at an increased risk for perinatal loss with type III CCAM. The purpose of this paper is to present our experience with the management of complicated types II and III CCAM with a novel technique: percutaneous ultrasound-guided fetal sclerotherapy (FST). METHODS: Three patients were referred with type II-III CCAM. Poor prognostic factors included hydrops, severe mediastinal shift, polyhydramnios and early gestational age (<26 weeks). Patients signed an informed consent. FST was performed with percutaneous injection of Ethamolin (ethanolamine oleate) or Polidocanol (aethoxysklerol) under ultrasound guidance using a 22-gauge needle. RESULTS: Resolution of hydrops and of the mass effect was observed in all cases without any complications. All patients were delivered at term. CONCLUSIONS: Fetal sclerotherapy is a novel approach to the management of complicated type II-III CCAM. Further studies are indicated to assess the risks and benefits of this innovative technique. |
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Authors:
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Carlos Bermúdez; Juan Pérez-Wulff; Mauricio Arcadipane; Gesualdo Bufalino; Libardo Gómez; Luis Flores; Cristian Sosa; Patricia W Bornick; Eftichia Kontopoulos; Rubén A Quintero |
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Publication Detail:
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Type: Case Reports; Evaluation Studies; Journal Article Date: 2008-08-28 |
Journal Detail:
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Title: Fetal diagnosis and therapy Volume: 24 ISSN: 1421-9964 ISO Abbreviation: Fetal. Diagn. Ther. Publication Date: 2008 |
Date Detail:
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Created Date: 2008-10-21 Completed Date: 2009-01-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9107463 Medline TA: Fetal Diagn Ther Country: Switzerland |
Other Details:
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Languages: eng Pagination: 237-40 Citation Subset: IM |
Copyright Information:
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Copyright 2008 S. Karger AG, Basel. |
Affiliation:
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Unidad de Perinatología, Hospital Universitario de Caracas, Universidad Central de Venezuela, Caracas, Venezuela. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cystic Adenomatoid Malformation of Lung, Congenital / therapy*, ultrasonography Female Fetal Diseases / therapy*, ultrasonography Gestational Age Humans Hydrops Fetalis / ultrasonography Pregnancy Sclerotherapy / methods* Ultrasonography, Prenatal |
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