Document Detail


Percutaneous excimer-laser and excimer-laser-assisted angioplasty of the lower extremities: results of initial clinical trial.
MedLine Citation:
PMID:  2526348     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Percutaneous peripheral excimer-laser angioplasty at 308 nm was used for treatment of 30 patients with peripheral vascular disease. Twenty-eight patients underwent laser-assisted balloon angioplasty, and two patients underwent laser angioplasty alone. Acute angiographic and clinical success was achieved in 24 of 31 (77%) femoropopliteal stenoses and occlusions. Seven of nine (78%) stenoses, six of seven (86%) short (0-5 cm) occlusions, seven of eight (88%) medium-length (6-10 cm) occlusions, three of four (75%) long (11-15 cm) occlusions, and one of three (33%) extreme (greater than 15 cm) occlusions were successfully treated. Inability to treat total occlusions was in each case related to a failure to maintain coaxial position and subintimal passage of the fiber. These cases demonstrate the feasibility of safely performing percutaneous peripheral excimer-laser or excimer-laser-assisted angioplasty. The overall frequency of restenosis after a mean follow-up period of 9.1 months was 29%. The data suggest that these procedures may be useful for the treatment of peripheral vascular disease in selected patients.
Authors:
F Litvack; W S Grundfest; L Adler; A E Hickey; J Segalowitz; L B Hestrin; F W Mohr; T Goldenberg; J S Laudenslager; J S Forrester
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Radiology     Volume:  172     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1989 Aug 
Date Detail:
Created Date:  1989-08-17     Completed Date:  1989-08-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  331-5     Citation Subset:  AIM; IM    
Affiliation:
Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Angiography
Angioplasty, Balloon / adverse effects,  methods*
Arterial Occlusive Diseases / radiography,  therapy
Clinical Trials as Topic
Female
Follow-Up Studies
Humans
Laser Therapy*
Leg / blood supply*
Male
Middle Aged
Recurrence
Grant Support
ID/Acronym/Agency:
5K0 HL01522/HL/NHLBI NIH HHS; 5K09 HL01381/HL/NHLBI NIH HHS; R29 HL38948/HL/NHLBI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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