| Percutaneous embolization on hereditary hemorrhagic telangiectasia patients with severe epistaxis. | |
| | |
MedLine Citation:
|
PMID: 19593974 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVES: To evaluate the results of embolization in patients with hereditary hemorrhagic telangiectasia (HHT) because of severe epistaxis. METHODS: All HHT patients who underwent an embolization (between 1992 and 2006) were asked to participate in this retrospective study. Twelve patients who had in total 19 embolization procedures were interviewed. A questionnaire was used assessing the frequency, severity, duration of epistaxis and their Impact on Lifestyle (IoL). Haemoglobin values were collected from the patients' records. Embolization of the pathologically enhancing lesions was performed using PVA particles. RESULTS: The direct effect of the embolization is very good in 95% of patients. The Impact factor (daily frequency x severity) of epistaxis improved in the first month (p = 0.000) and one year after embolization (p = 0.009). Eleven embolizations (61%) were still associated with significant improvement. There was a reduction in the duration of epistaxis by 16 minutes per day one month after embolization (p = 0.005). However, this reduction was not found one year after embolization. Mean haemoglobin rose significantly after 1 year by an average of 0.8 mmol/l (p = 0.045). Impact on Lifestyle improved in 68% of the procedures and was unchanged in 32%. CONCLUSION: Embolizations remain a therapeutic option in experienced hands. The indication should be made carefully, because of possible (major) complications. |
| | |
Authors:
|
S J Braak; C A de Witt; F J M Disch; T Th C Overtoom; J J Westermann |
Related Documents
:
|
8410004 - Chiari malformation in adults: relation of morphological aspects to clinical features a... 17674294 - Comparison of frame-based and frameless stereotactic hematoma puncture and subsequent f... 8683264 - Recurrent cerebral arteriovenous malformations after negative postoperative angiograms. 23602084 - Monitoring of hiv viral load, cd4 cell count, and clinical assessment versus clinical m... 23562754 - Optimized non-bismuth quadruple therapies cure most patients with helicobacter pylori i... 8959564 - Influence of smoking on long-term clinical results of intrabony defects treated with re... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Rhinology Volume: 47 ISSN: 0300-0729 ISO Abbreviation: Rhinology Publication Date: 2009 Jun |
Date Detail:
|
Created Date: 2009-07-14 Completed Date: 2009-08-20 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0347242 Medline TA: Rhinology Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 166-71 Citation Subset: IM |
Affiliation:
|
Department of Radiology, St Antonius Hospital, Nieuwegein, The Netherlands. sjbraak@gmail.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Embolization, Therapeutic
/
methods* Epistaxis / etiology*, therapy* Female Humans Male Middle Aged Questionnaires Retrospective Studies Severity of Illness Index Statistics, Nonparametric Telangiectasia, Hereditary Hemorrhagic / complications* Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Olfactory detection thresholds and pleasantness of a food-related and a non-food odour in hunger and...
Next Document: Evaluation of prognostic factors for olfaction in nasal polyposis treated by endoscopic sinus surger...