| Percutaneous coronary intervention in the current era compared with 1985-1986: the National Heart, Lung, and Blood Institute Registries. | |
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MedLine Citation:
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PMID: 11113044 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Although refinements have occurred in coronary angioplasty over the past decade, little is known about whether these changes have affected outcomes. METHODS AND RESULTS: Baseline features and in-hospital and 1-year outcomes of 1559 consecutive patients in the 1997-1998 Dynamic Registry who were having first coronary intervention were compared with 2431 patients in the 1985-1986 National Heart, Lung, and Blood Institute Registry. Compared with patients in the 1985-1986 Registry, Dynamic Registry patients were older (mean age, 62 versus 58 years; P:<0.001) and more often female (32.1% versus 25.5%; P:<0.001). In the Dynamic Registry, procedures were more often performed for acute myocardial infarction (22.9% versus 9.9%; P:<0.001) and treated lesions were more severe (84.5% versus 82.5% diameter reduction; P:<0.001), thrombotic (22.1% versus 11.3%; P:<0.001) or calcified (29.5% versus 10.8%; P:<0.001). Stents were used in 70.5% of Dynamic Registry patients, whereas 1985-1986 patients received balloon angioplasty alone. Procedural success was higher in the Dynamic Registry (92.0% versus 81.8%; P:<0.001) and the rate of in-hospital death, myocardial infarction, and emergency coronary bypass surgery combined was lower (4.9% versus 7.9%; P:=0.001) than in the 1985-1986 Registry. The 1-year rate for CABG was lower in the Dynamic Registry (6.9% versus 12.6%; P:<0.001). CONCLUSIONS: Although Dynamic Registry patients had more unstable and complex coronary disease than those in the 1985-1986 Registry, their rate of procedural success was higher whereas rates of complications and subsequent CABG were lower. Results of percutaneous coronary intervention have improved substantially over the past decade. |
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Authors:
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D O Williams; R Holubkov; W Yeh; M G Bourassa; M Al-Bassam; P C Block; P Coady; H Cohen; M Cowley; G Dorros; D Faxon; D R Holmes; A Jacobs; S F Kelsey; S B King; R Myler; J Slater; V Stanek; H A Vlachos; K M Detre |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Circulation Volume: 102 ISSN: 1524-4539 ISO Abbreviation: Circulation Publication Date: 2000 Dec |
Date Detail:
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Created Date: 2000-12-18 Completed Date: 2001-01-04 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0147763 Medline TA: Circulation Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 2945-51 Citation Subset: IM |
Affiliation:
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Division of Cardiology, Rhode Island Hospital, Brown University, Providence, RI, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Angioplasty, Transluminal, Percutaneous Coronary* Coronary Disease / ethnology, therapy* Female Humans Male Middle Aged Multicenter Studies as Topic Registries Treatment Outcome |
| Grant Support | |
ID/Acronym/Agency:
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HL33292-14/HL/NHLBI NIH HHS |
| Comments/Corrections | |
Comment In:
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Circulation. 2000 Dec 12;102(24):2910-4
[PMID:
11113038
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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