| Percutaneous central venous catheter colonization with Malassezia furfur: incidence and clinical significance. | |
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MedLine Citation:
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PMID: 3658573 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Malassezia furfur colonization of central venous catheters has been implicated in the pathogenesis of systemic infections with this lipid-dependent yeast. To determine the incidence of catheter colonization in our neonatal intensive care unit (NICU), 25 consecutively removed percutaneous central venous catheters were examined by rinsing the lumen with saline and plating the rinse fluid on Sabouraud dextrose agar overlaid with olive oil. M furfur grew from the lumina of eight catheters (32%). Surveillance skin cultures were performed in the NICU on two occasions to determine the prevalence of skin colonization with M furfur. M furfur was found on the skin of 64% of the infants. In contrast, only 3% (1/33) of healthy, nonhospitalized infants 2 to 8 weeks of age had skin colonized with M furfur. During the 5-month study period, two NICU infants had evidence of systemic infection with M furfur. We conclude that M furfur frequently colonizes both the skin and percutaneous central venous catheters in NICU infants. Further studies are needed to determine the relationship between skin colonization and catheter colonization, and the factors contributing to systemic disease with this organism. |
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Authors:
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J L Aschner; A Punsalang; W M Maniscalco; M A Menegus |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Pediatrics Volume: 80 ISSN: 0031-4005 ISO Abbreviation: Pediatrics Publication Date: 1987 Oct |
Date Detail:
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Created Date: 1987-11-02 Completed Date: 1987-11-02 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0376422 Medline TA: Pediatrics Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 535-9 Citation Subset: AIM; IM |
Affiliation:
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Department of Pediatrics, University of Rochester Medical Center, New York. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors Blood / microbiology Catheterization, Central Venous / adverse effects, instrumentation* Equipment Contamination* Humans Infant, Newborn Infant, Premature Intensive Care Units, Neonatal Malassezia / isolation & purification* Male Mycoses / etiology Prospective Studies Skin / microbiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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