Document Detail

Percutaneous biliary drainage: clinical trial of analgesia with interpleural block.
MedLine Citation:
PMID:  9393518     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To determine the analgesic efficacy and safety of interpleural block for percutaneous biliary drainage. MATERIALS AND METHODS: In this double-blind study, 34 age- and sex-matched patients who were to undergo percutaneous biliary drainage because of malignant biliary obstruction were randomly assigned to the true-block group (30 mL 0.5% bupivacaine block) or placebo-block group; all had access to a patient-controlled analgesia (fentanyl) pump. Self medication, pain reports, blood pressure, heart rate, and oxygen saturation were monitored during and until 8 hours after drainage. The McGill Pain Questionnaire was administered 1 hour after biliary drainage. RESULTS: Patients in the placebo group self administered statistically significantly more fentanyl than did patients in the true-block group (P = .008). Peak pain scores (10-point scale) and McGill Pain Questionnaire scores were statistically significantly higher for the placebo group patients (P = .017 and P = .001, respectively). There were no differences between groups in terms of blood pressure, heart rate, and oxygen saturation. Two patients had pneumothorax caused by the interpleural block. CONCLUSION: Interpleural block was effective in decreasing pain and opioid requirements during and after percutaneous biliary drainage and did not compromise the cardiopulmonary status of the patient. However, the rate of pneumothorax was higher than previously reported.
E Therasse; M Choinière; G Soulez; V L Oliva; P Rousseau; F Fugère; D Boudreault; J R Cusson
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Radiology     Volume:  205     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1997 Dec 
Date Detail:
Created Date:  1997-12-30     Completed Date:  1997-12-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  663-8     Citation Subset:  AIM; IM    
Department of Radiology, University of Montreal Medical Center, Quebec, Canada.
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MeSH Terms
Analgesia* / adverse effects,  methods
Analgesia, Patient-Controlled
Analgesics, Opioid
Anesthetics, Local*
Cholestasis / therapy*
Double-Blind Method
Drainage / methods*
Nerve Block* / adverse effects,  methods
Pain Measurement
Pneumothorax / etiology
Reg. No./Substance:
0/Analgesics, Opioid; 0/Anesthetics, Local; 2180-92-9/Bupivacaine; 437-38-7/Fentanyl

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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