Document Detail

Percutaneous ablative treatment of metastatic bone tumours: visual analogue scale scores in a short-term series.
MedLine Citation:
PMID:  21451927     Owner:  NLM     Status:  In-Data-Review    
Introduction: The aim of this study was to examine the role of palliative percutaneous secondary lesions bone treatment by comparing the visual analogue scale (VAS) scores of cryoablation plus vertebroplasty versus radiofrequency (RF) plus vertebroplasty so as to determine their feasibility, reliability and efficacy in a short-term series. Methods: Combined RF thermal ablation plus osteoplasty or cryoablation plus osteoplasty was performed in osteolytic secondary bone localisations in 30 consecutive patients who were suffering from pain refractory to conservative therapies. We evaluated pain with the VAS during the preoperative period and at four hours, 24 hours, one week, one month, three months and six months post procedure. Results: There were no statistically significant differences in the VAS score between patients treated with cryoablation plus osteoplasty and those treated with RF ablation plus osteoplasty at one week (p-value is 0.34), one month (p-value is 1), three months (p-value is 0.68) and six months (p-value is 0.65) post procedure. Patients treated with cryoablation plus vertebroplasty have less pain at four hours (p-value less than 0.001) and 24 hours (p-value less than 0.001) than patients treated with RF ablation plus vertebroplasty. Conclusion: Both RF ablation and cryoablation are optimal techniques in the treatment of painful bone metastatic cancer. Cryoablation achieves less treatment-related pain during the early period of follow-up and better volume control by real-time depiction of ablation margins.
S Masala; G Guglielmi; M C Petrella; R Mastrangeli; A Meschini; G C Anselmetti; D A Bartolucci; M Mammucari; G Manenti; G Simonetti
Related Documents :
20825817 - A point-of-care chemistry test for reduction of turnaround and clinical decision time.
15236277 - 4s neuroblastoma: the long-term outcome.
14745327 - Abdominal drainage after hepatic resection is contraindicated in patients with chronic ...
21191297 - Changing the topography of acne with topical medications.
22972047 - Percutaneous transluminal balloon angioplasty and stenting for carotid artery stenosis.
24022067 - A multidisciplinary intervention to reduce antibiotic duration in lower respiratory tra...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Singapore medical journal     Volume:  52     ISSN:  0037-5675     ISO Abbreviation:  Singapore Med J     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-03-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0404516     Medline TA:  Singapore Med J     Country:  Singapore    
Other Details:
Languages:  eng     Pagination:  182-9     Citation Subset:  IM    
Department of Diagnostic Imaging and Interventional Radiology, Molecular Imaging and Radiotheraphy, Policlinico Universitario Tor Vergata, Roma 00133, Italy.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Comparison of haematological parameters in patients with non-alcoholic fatty liver disease and alcoh...
Next Document:  Pemetrexed in the treatment of thoracic malignancies: a single centre experience in Singapore.