Document Detail


Perceptual and physiologic responses during treadmill and cycle exercise in patients with COPD.
MedLine Citation:
PMID:  18753470     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Although the cycle ergometer is the traditional mode for exercise testing in patients with respiratory disease, this preference over the treadmill does not consider perceptual responses. Our hypotheses were as follows: (1) the regression slope between breathlessness and oxygen consumption (Vo(2)) is greater on the treadmill than on the cycle ergometer; and (2) the regression slope between leg discomfort and Vo(2) is greater on the cycle ergometer than on the treadmill. METHODS: Twenty patients (10 men/10 women) with COPD (mean +/- SD postbronchodilator FEV(1), 50 +/- 15% of predicted) used a continuous method to report changes in breathlessness and in leg discomfort during cycle and treadmill exercise. RESULTS: Patients reported an earlier onset of breathlessness and leg discomfort during cycling. Peak ratings of breathlessness were higher on the treadmill, whereas peak ratings of leg discomfort were higher on the cycle ergometer. The regression slopes for breathlessness as a function of Vo(2) and of minute ventilation (Ve) were higher on the treadmill. The regression slopes between leg discomfort and Vo(2) were similar for treadmill and cycle exercise. Peak Vo(2) was significantly higher with treadmill exercise (mean Delta = 8%; p = 0.002). CONCLUSIONS: Patients with COPD exhibit different perceptual and physiologic responses during treadmill walking and cycling. Although ratings of breathlessness are initially higher with cycling at equivalent levels of Vo(2), the changes in breathlessness as a function of physiologic stimuli (Vo(2) and Ve) are greater during treadmill exercise. Leg discomfort is the predominant symptom throughout cycling.
Authors:
James A Murray; Laurie A Waterman; Joseph Ward; John C Baird; Donald A Mahler
Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2008-08-27
Journal Detail:
Title:  Chest     Volume:  135     ISSN:  1931-3543     ISO Abbreviation:  Chest     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-02-09     Completed Date:  2009-04-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  United States    
Other Details:
Languages:  eng     Pagination:  384-90     Citation Subset:  AIM; IM    
Affiliation:
Unity Health System, Rochester, NY, USA.
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MeSH Terms
Descriptor/Qualifier:
Adaptation, Physiological
Aged
Bicycling / physiology*
Cohort Studies
Exercise Test*
Exercise Tolerance
Female
Forced Expiratory Volume
Humans
Lung Compliance / physiology
Male
Middle Aged
Oxygen Consumption / physiology*
Perception / physiology*
Pulmonary Disease, Chronic Obstructive / diagnosis,  physiopathology*
Pulmonary Ventilation / physiology
Respiratory Function Tests
Sampling Studies
Sensitivity and Specificity
Severity of Illness Index
Walking / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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