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Perceptual Inference Predicts Contextual Modulations of Sensory Responses.
MedLine Citation:
PMID:  22442081     Owner:  NLM     Status:  Publisher    
Sensory receptive fields (RFs) vary as a function of stimulus properties and measurement methods. Previous stimuli or surrounding stimuli facilitate, suppress, or change the selectivity of sensory neurons' responses. Here, we propose that these spatiotemporal contextual dependencies are signatures of efficient perceptual inference and can be explained by a single neural mechanism, input targeted divisive inhibition. To respond both selectively and reliably, sensory neurons should behave as active predictors rather than passive filters. In particular, they should remove input they can predict ("explain away") from the synaptic inputs to all other neurons. This implies that RFs are constantly and dynamically reshaped by the spatial and temporal context, while the true selectivity of sensory neurons resides in their "predictive field." This approach motivates a reinvestigation of sensory representations and particularly the role and specificity of surround suppression and adaptation in sensory areas.
Timm Lochmann; Udo A Ernst; Sophie Denève
Publication Detail:
Journal Detail:
Title:  The Journal of neuroscience : the official journal of the Society for Neuroscience     Volume:  32     ISSN:  1529-2401     ISO Abbreviation:  -     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-3-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8102140     Medline TA:  J Neurosci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  4179-4195     Citation Subset:  -    
Group for Neural Theory, Département d'Études Cognitives, École normale supérieure, Collège de France, Paris 75005, France, Neural Information Processing Group, Department of Software Engineering and Theoretical Computer Science, Technische Universität Berlin, Berlin 10587, Germany, and Institute of Theoretical Neurophysics, Department of Physics, University of Bremen, Bremen 28334, Germany.
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