Document Detail


Percentage distribution of fatty acids in subcutaneous adipose tissue of patients with peptic ulcer disease.
MedLine Citation:
PMID:  8416668     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Dietary linoleic acid has been implicated in the pathogenesis of peptic ulcer disease because its metabolite arachidonic acid may be converted to cytoprotective prostaglandins. In addition, it has been suggested that the falling incidence and virulence of duodenal ulcer disease is related to increased dietary polyunsaturated essential fatty acid intake. In the present study the percentage content of linoleic acid in subcutaneous adipose tissue microbiopsies were used to see whether changes in percentage of fatty acids correlate with the presence or absence of an ulcer in individual patients. No significant difference in the adipose tissue content of linoleic acid was found, ie, 11.2 +/- 0.7% (n = 15) vs 10.9 +/- 0.5% (n = 15) in patients with peptic ulcer disease and matched control subjects, respectively.
Authors:
K N Seidelin; S Meisner; K Bukhave
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  57     ISSN:  0002-9165     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  1993 Jan 
Date Detail:
Created Date:  1993-01-21     Completed Date:  1993-01-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  70-2     Citation Subset:  AIM; IM    
Affiliation:
Department of Surgical Gastroenterology, Bispebjerg Hospital, University of Copenhagen, Denmark.
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MeSH Terms
Descriptor/Qualifier:
Adipose Tissue / chemistry*
Fatty Acids / analysis*
Female
Humans
Linoleic Acid
Linoleic Acids / analysis
Male
Middle Aged
Peptic Ulcer / metabolism*
Skin
Smoking
Chemical
Reg. No./Substance:
0/Fatty Acids; 0/Linoleic Acids; 2197-37-7/Linoleic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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