| Percent achieved of predicted peak exercise oxygen uptake and kinetics of recovery of oxygen uptake after exercise for risk stratification in chronic heart failure. | |
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MedLine Citation:
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PMID: 9688429 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To investigate whether percent achieved of predicted peak exercise oxygen uptake (%VO2max) and recovery of oxygen consumption after exercise may provide prognostic information in chronic heart failure (CHF), we prospectively studied 196 patients with mild to moderate CHF. The following variables were examined: age, etiology of CHF, functional class, ejection fraction (EF), peak exercise oxygen uptake normalized for body weight (VO2max), %VO2max, time to reach 50% of the peak oxygen uptake after exercise (T1/2VO2max), presence of nonsustained ventricular tachycardia (NSVT) and inability to take ACE-inhibitors. VO2max was the most powerful predictor of cardiac death (P<0.0001). Other independent predictors of death were EF, T1/2VO2max, NSVT and inability to take ACE-inhibitors. The discriminatory accuracy of VO2max for cardiac death was not significantly greater than that of %VO2max. In conclusion, the determination of %VO2max does not enhance risk stratification in CHF whereas the kinetics of oxygen consumption after exercise can provide prognostic information. |
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Authors:
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D Scrutinio; A Passantino; R Lagioia; F Napoli; A Ricci; P Rizzon |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: International journal of cardiology Volume: 64 ISSN: 0167-5273 ISO Abbreviation: Int. J. Cardiol. Publication Date: 1998 Apr |
Date Detail:
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Created Date: 1998-09-29 Completed Date: 1998-09-29 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8200291 Medline TA: Int J Cardiol Country: IRELAND |
Other Details:
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Languages: eng Pagination: 117-24 Citation Subset: IM |
Affiliation:
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Division of Cardiology, S. Maugeri Foundation, IRCCS, Rehabilitation Institute of Cassano M., Bari, Italy. clinlavc@mbox.vol.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Exercise Test Female Heart Failure / metabolism*, mortality Humans Male Middle Aged Oxygen / pharmacokinetics Oxygen Consumption* Prognosis Risk Statistics as Topic Survival Analysis |
| Chemical | |
Reg. No./Substance:
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7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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