| Perceived maternal stress during pregnancy and its relation to infant stress reactivity at 2 days and 10 months of postnatal life. | |
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MedLine Citation:
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PMID: 20080522 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Although the negative impact of maternal stress during pregnancy on stress reactivity in offspring is well documented in nonhuman animals, we know little about these relations in humans and their lasting effects. AIM: The authors examined the relation between perceived maternal stress during pregnancy and stability of infant stress reactivity across the first year of postnatal life in humans. STUDY DESIGN: Perceived maternal stress during pregnancy was measured in the immediate postpartum period and again at 10 months after delivery in 84 mothers and examined in relation to behavioral and neuroendocrine stress reactivity measures in their healthy, full-term infants. OUTCOME MEASURES: Salivary cortisol was collected between 24 to 48 hours of postnatal life in response to a heel stick and again at 10 months of age in response to a toy removal task in the same sample of infants. Behavioral reactivity was coded from direct observation during the toy removal task. RESULTS: Perceived maternal stress during pregnancy and neonatal cortisol reactivity each remained stable across the first 10 months of postnatal life. Maternal stress during pregnancy predicted infant cortisol reactivity at 2 days and 10 months after birth as well as behavioral reactivity at 10 months. Neonatal cortisol reactivity predicted 10-month behavioral reactivity. CONCLUSION: These preliminary findings suggest that maternal stress during pregnancy may negatively affect neonatal stress reactivity within 24 to 48 hours after birth, and these influences may persist through the first year of postnatal life. |
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Authors:
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Eman Leung; Susan L Tasker; Leslie Atkinson; Tracy Vaillancourt; Jay Schulkin; Louis A Schmidt |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Clinical pediatrics Volume: 49 ISSN: 1938-2707 ISO Abbreviation: Clin Pediatr (Phila) Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-01-18 Completed Date: 2010-05-06 Revised Date: 2011-08-25 |
Medline Journal Info:
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Nlm Unique ID: 0372606 Medline TA: Clin Pediatr (Phila) Country: United States |
Other Details:
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Languages: eng Pagination: 158-65 Citation Subset: AIM; IM |
Affiliation:
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McMaster University, Ontario, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Age Factors Child Development / physiology Cohort Studies Female Humans Hydrocortisone / metabolism Hypothalamo-Hypophyseal System / physiology Infant Infant Behavior / physiology* Infant, Newborn / physiology*, psychology* Male Pituitary-Adrenal System / physiology Pregnancy Pregnancy Complications / diagnosis, etiology, psychology* Risk Factors Stress, Physiological / physiology* Stress, Psychological / complications*, diagnosis, psychology Young Adult |
| Chemical | |
Reg. No./Substance:
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50-23-7/Hydrocortisone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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