Document Detail

Per rectal portal scintigraphy as a useful tool for predicting esophageal variceal bleeding in cirrhotic patients.
MedLine Citation:
PMID:  17278205     Owner:  NLM     Status:  MEDLINE    
AIM: To investigate potential roles of per rectal portal scintigraphy in diagnosis of esophageal varices and predicting the risk of bleeding.
METHODS: Fifteen normal subjects and fifty cirrhotic patients with endoscopically confirmed esophageal varices were included. Patients were categorized into bleeder and non-bleeder groups according to history of variceal bleeding. All had completed per rectal portal scintigraphy using (99m)Technetium pertechnetate. The shunt index was calculated from the ratio of (99m)Technetium pertechnetate in the heart and the liver. Data were analyzed using Student's t-test and receiver operating characteristics.
RESULTS: Cirrhotic patients showed a higher shunt index than normal subjects (63.80 +/- 25.21 vs 13.54 +/- 6.46, P < 0.01). Patients with variceal bleeding showed a higher shunt index than those without bleeding (78.45 +/- 9.40 vs 49.35 +/- 27.72, P < 0.01). A shunt index of over 20% indicated the presence of varices and that of over 60% indicated the risk of variceal bleeding.
CONCLUSION: In cirrhotic patients, per rectal portal scintigraphy is a clinically useful test for identifying esophageal varices and risk of variceal bleeding.
Taned Chitapanarux; Ong-ard Praisontarangkul; Satawat Thongsawat; Pises Pisespongsa; Apinya Leerapun
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  World journal of gastroenterology : WJG     Volume:  13     ISSN:  1007-9327     ISO Abbreviation:  World J. Gastroenterol.     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-02-05     Completed Date:  2007-03-27     Revised Date:  2014-09-07    
Medline Journal Info:
Nlm Unique ID:  100883448     Medline TA:  World J Gastroenterol     Country:  China    
Other Details:
Languages:  eng     Pagination:  791-5     Citation Subset:  IM    
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MeSH Terms
Esophageal and Gastric Varices / epidemiology,  radionuclide imaging*
Gastrointestinal Hemorrhage / epidemiology,  radionuclide imaging*
Liver Cirrhosis / epidemiology*
Middle Aged
Portal System / radionuclide imaging*
Predictive Value of Tests
Radionuclide Imaging / methods
Radiopharmaceuticals / diagnostic use
Risk Factors
Sodium Pertechnetate Tc 99m / diagnostic use
Reg. No./Substance:
0/Radiopharmaceuticals; A0730CX801/Sodium Pertechnetate Tc 99m

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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