| Peptide YY secretion in morbidly obese patients before and after vertical banded gastroplasty. | |
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MedLine Citation:
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PMID: 12082881 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The Peptide YY (PYY) secretion pattern was assessed in morbidly obese (MO) patients before and after vertical banded gastroplasty (VBG). METHODS: 12 MO patients (10 women, 2 men) age 29-62 years, BMI 50.7 +/- 9.6 kg/m2, treated with a VBG were studied. Before surgery, blood samples were taken in basal conditions of fasting and 10, 15, 20, 30 and 60 min after the ingestion of a semiliquid test meal. This was repeated in the same patients 6 and 12 months after VBG. Blood samples were also taken from 6 healthy non-obese subjects as controls. PYY plasma concentration was measured by radioimmunoassay with I125. RESULTS: There were statistically significant differences between the preoperative PYY concentration in MO patients compared to controls. After a VBG, PYY concentration varied significantly compared to the preoperative levels. There was no significant difference between the PYY concentrations in the MO patients after VBG and the controls. CONCLUSION: PYY concentration is lower in MO patients compared with non-obese. After VBG, PYY concentration gradually rises to the control levels. |
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Authors:
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Mercedes Alvarez Bartolomé; María Borque; Javier Martinez-Sarmiento; Eugenio Aparicio; Carmen Hernández; Lucio Cabrerizo; J A Fernández-Represa |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Obesity surgery Volume: 12 ISSN: 0960-8923 ISO Abbreviation: Obes Surg Publication Date: 2002 Jun |
Date Detail:
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Created Date: 2002-06-26 Completed Date: 2002-12-13 Revised Date: 2007-12-05 |
Medline Journal Info:
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Nlm Unique ID: 9106714 Medline TA: Obes Surg Country: Canada |
Other Details:
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Languages: eng Pagination: 324-7 Citation Subset: IM |
Affiliation:
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Department of Surgery, Hospital Clínico San Carlos, C/Martín Lagos s/n, 28040 Madrid, Spain. alvarezrepresa@hotmail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Body Mass Index Female Gastroplasty* Humans Male Middle Aged Obesity, Morbid / blood*, physiopathology, surgery* Peptide YY / blood*, secretion* Postoperative Period Radioimmunoassay Time Factors Weight Loss / physiology |
| Chemical | |
Reg. No./Substance:
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106388-42-5/Peptide YY |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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