Document Detail

Pentraxin 3 values during normal pregnancy.
MedLine Citation:
PMID:  20852923     Owner:  NLM     Status:  In-Data-Review    
Pentraxin 3 (PTX3) is an inflammatory molecule that has been reported to be a promising early biomarker for subsequent preeclampsia. The levels of PTX3 vary during pregnancy and it is thus a need to establish reference intervals during normal pregnancy. Repeated blood samples were collected from 52 healthy pregnant females. The samples were divided according to collection time into the following groups: week 7-17, week 17-24, week 24-28, week 28-31, week 31-34, week 34-38, before delivery and after delivery. The samples were analyzed for PTX3 with a sandwich ELISA and the 2.5 and 97.5 percentiles for each sample period was calculated. There was a continuous increase of serum PTX3 as pregnancy progressed. The increase was most evident after week 31 with the highest levels just before delivery.
Anders Larsson; Maria Palm; Johanna Helmersson; Ove Axelsson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Inflammation     Volume:  34     ISSN:  1573-2576     ISO Abbreviation:  Inflammation     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-09-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7600105     Medline TA:  Inflammation     Country:  United States    
Other Details:
Languages:  eng     Pagination:  448-51     Citation Subset:  IM    
Department of Medical Sciences, Clinical Chemistry, Uppsala University Hospital, 751 85, Uppsala, Sweden,
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