Document Detail

Pentose synthesis in glucose-grown cells of Lactobacillus casei.
MedLine Citation:
PMID:  2111278     Owner:  NLM     Status:  MEDLINE    
The pathway of pentose synthesis in glucose-grown cells of Lactobacillus casei was ascertained. Glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase were present in glucose-grown cells, while transaldolase and transketolase were present only in traces. This suggested that only the oxidative arm of this pathway was operative in glucose-grown cells. On the other hand, in ribose-grown cells, transaldolase was induced with a concomitant suppression of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase. These results were confirmed by the detection of labelled CO2 produced by L. casei grown on [1-14C]glucose. The activities of the enzymes of the oxidative pentose phosphate pathway as also the rate of CO2 formation were higher in the exponential phase of growth as compared to the stationary phase, when the requirement of the cells for pentoses for the formation of DNA and RNA was higher.
L Menezes; S M Kelkar; G S Kaklij
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of biochemistry & biophysics     Volume:  27     ISSN:  0301-1208     ISO Abbreviation:  Indian J. Biochem. Biophys.     Publication Date:  1990 Feb 
Date Detail:
Created Date:  1990-06-25     Completed Date:  1990-06-25     Revised Date:  2000-12-18    
Medline Journal Info:
Nlm Unique ID:  0310774     Medline TA:  Indian J Biochem Biophys     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  18-22     Citation Subset:  IM    
Biochemistry Division, Bhabha Atomic Research Centre, Bombay.
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MeSH Terms
Glucose / metabolism*
Lactobacillus casei / growth & development,  metabolism*
Pentoses / biosynthesis*
Reg. No./Substance:
0/Pentoses; 50-99-7/Glucose

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