Document Detail

Penile Veins are the Principal Component in Erectile Rigidity: A Study of Penile Venous Stripping on Defrosted Human Cadavers.
MedLine Citation:
PMID:  22604630     Owner:  NLM     Status:  Publisher    
The human erectile mechanism is an intricate interplay of hormonal, vascular, neurological, sinusoidal, pharmacological, and psychological factors. However, the relative influence of each respective component remains somewhat unclear, and merits further study. We investigated the role of venous outflow in an attempt to isolate the key determinant of erectile function. Dynamic infusion cavernosometry and cavernosography was conducted on fifteen defrosted human cadavers, both before and after the systematic removal and ligation of erection-related penile veins. Preoperatively, an infusion rate of <28.1 mL/min (from <14.0-85.0) was required to induce a rigid erection (defined as intracavernosal pressure [ICP] exceeding 90 mmHg). Following surgery, we were able to obtain the same result at a rate of 7.3 mL/min (from 3.1-13.5) across the entire sample. Thus, we witnessed statistically significant postoperative differences (all p ≤ 0.01), consistently remarking increased ICP, lower perfusion volumes, and a general reduction in time taken to attain rigidity. The cavernosograms provided further evidence substantiating the critical role played by erection-related veins, while histological samples confirmed the postoperative integrity of the corpora cavernosa. Given that our use of cadavers eliminated the influence of hormonal, arterial, neurological, sinusoidal, pharmacological, and psychological factors, we believe that our study demonstrates that the human erection is fundamentally a mechanical event contingent on venous competence.
Geng-Long Hsu; Yi-Ping Huang; Mang-Hung Tsai; Cheng-Hsing Hsieh; Heng-Shuen Chen; Eugen Molodysky; Chi Can Huynh; Hong-Jeng Yu
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-17
Journal Detail:
Title:  Journal of andrology     Volume:  -     ISSN:  1939-4640     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8106453     Medline TA:  J Androl     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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