Document Detail


Penicillamine-induced ocular myasthenia gravis in rheumatoid arthritis.
MedLine Citation:
PMID:  2144538     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a case of a 47-year-old woman with rheumatoid arthritis who developed ocular myasthenia gravis during penicillamine treatment. Her serum contained elevated titers of acetylcholine receptor antibodies, and her symptoms resolved 8 weeks after discontinuation of penicillamine. We review the clinical and laboratory features of this syndrome of penicillamine-induced myasthenia gravis and discuss its pathophysiology and treatment.
Authors:
G T Liu; D C Bienfang
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of clinical neuro-ophthalmology     Volume:  10     ISSN:  0272-846X     ISO Abbreviation:  J Clin Neuroophthalmol     Publication Date:  1990 Sep 
Date Detail:
Created Date:  1990-10-17     Completed Date:  1990-10-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8109051     Medline TA:  J Clin Neuroophthalmol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  201-5     Citation Subset:  IM    
Affiliation:
Division of Neurology, Brigham and Women's Hospital, Boston, MA 02115.
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MeSH Terms
Descriptor/Qualifier:
Arthritis, Rheumatoid / complications*,  drug therapy,  physiopathology
Diplopia / chemically induced,  complications,  physiopathology
Female
Humans
Middle Aged
Myasthenia Gravis / chemically induced*,  complications,  physiopathology
Ocular Motility Disorders / chemically induced*,  complications,  physiopathology
Oculomotor Muscles / drug effects
Penicillamine / adverse effects*
Receptors, Cholinergic / blood
Chemical
Reg. No./Substance:
0/Receptors, Cholinergic; 52-67-5/Penicillamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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