| Penetration of digoxin into cerebrospinal fluid. | |
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MedLine Citation:
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PMID: 1012999 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The concentration of digoxin in the cerebrospinal fluid (CSF) of ten patients receiving conventional oral doses of this cardiac glycoside has been measured by a radioimmunoassay technique. Digoxin was undetected in eight patients and barely detectable in two, suggesting the presence of a significant blood-CSF barrier for digoxin. The implication of these findings is discussed. |
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Authors:
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G D Schott; D W Holt; A M Hayler |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Postgraduate medical journal Volume: 52 ISSN: 0032-5473 ISO Abbreviation: Postgrad Med J Publication Date: 1976 Nov |
Date Detail:
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Created Date: 1977-03-15 Completed Date: 1977-03-15 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0234135 Medline TA: Postgrad Med J Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 700-2 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Blood-Brain Barrier Digoxin / blood, cerebrospinal fluid* Female Humans Male Middle Aged |
| Chemical | |
Reg. No./Substance:
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20830-75-5/Digoxin |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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