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Pemphigoid gestationis.
MedLine Citation:
PMID:  21163161     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Pemphigoid gestationis is a rare autoimmune blistering disease of pregnancy. It is characterized by pruritic, urticarial plaques with the development of tense vesicles and bullae within the lesions. Pemphigoid gestationis has been associated with premature delivery, small-for-gestational-age infants. Recurrences with subsequent pregnancies are often more severe. Oral glucocorticoids are the mainstay of therapy. Differentiation of pemphigoid gestationis from pruritic urticarial papules and plaques of pregnancy is essential because management and outcomes differ. In instances in which clinical diagnosis is difficult, direct immunofluorescence tests, immunoblots, or ELISA studies of anti-basement-membrane zone antibodies are useful in establishing the diagnosis.
Authors:
Phoebe D Lu; Jonathan Ralston; Hideko Kamino; Jennifer A Stein
Publication Detail:
Type:  Journal Article     Date:  2010-11-15
Journal Detail:
Title:  Dermatology online journal     Volume:  16     ISSN:  1087-2108     ISO Abbreviation:  Dermatol. Online J.     Publication Date:  2010  
Date Detail:
Created Date:  2010-12-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610776     Medline TA:  Dermatol Online J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  10     Citation Subset:  IM    
Affiliation:
Department of Dermatology, New York University, New York, NY, USA.
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