| Pelvic organ dysfunction is more prevalent and severe in MSA-P compared to Parkinson's disease. | |
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MedLine Citation:
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PMID: 20658542 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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AIMS: It is usually difficult to distinguish between idiopathic Parkinson's disease (PD) and parkinsonian-type multiple system atrophy (MSA-P) in the early stage. However, it is important to make a careful early-stage diagnosis. Therefore, we determined whether an examination of pelvic organ dysfunction would be helpful to distinguish between PD and MSA-P. METHODS: We recruited 61 patients with PD and 54 patients with MSA-P who were examined at our neurology clinic. The mean ages of the patients with PD and MSA-P were 67 and 64 years, respectively. The mean disease duration of both groups was 3.2 years. We administered a questionnaire on pelvic organ dysfunction to the PD and MSA-P groups. The questionnaire had sections focusing on bladder, bowel, and sexual function. Dysfunction, as described in the responses, was evaluated as normal, mild (>once a month), moderate (>once a week), or severe (>once a day). The Mann-Whitney U-test was used for statistical analysis. RESULTS: Compared with the PD group, the prevalence and severity of pelvic dysfunction in the MSA-P group was significantly higher for urinary urgency (MSA-P 76%, PD 58%, P<0.05), retardation in initiating urination (79%, 48%, P<0.05), prolongation in urination (79%, 72%, P<0.05), and constipation (58%, 31%, P<0.05). The quality-of-life index among pelvic organ dysfunctions indicated that urinary and bowel function was significantly more impaired in the MSA-P group than in the PD group. CONCLUSIONS: Urinary urgency, retardation in initiating urination, prolongation in urination, and constipation are more prevalent and severe in MSA-P compared to PD. |
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Authors:
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T Yamamoto; R Sakakibara; T Uchiyama; C Yamaguchi; F Nomura; T Ito; M Yanagisawa; M Yano; Y Awa; T Yamanishi; T Hattori; S Kuwabara |
Publication Detail:
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Type: Journal Article Date: 2010-07-23 |
Journal Detail:
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Title: Neurourology and urodynamics Volume: 30 ISSN: 1520-6777 ISO Abbreviation: Neurourol. Urodyn. Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2010-12-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8303326 Medline TA: Neurourol Urodyn Country: United States |
Other Details:
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Languages: eng Pagination: 102-7 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Wiley-Liss, Inc. |
Affiliation:
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Department of Neurology, Graduate School of Medicine, Chiba University, Chiba, Japan. tatsuya-yamamoto@mbc.nifty.com |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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