Document Detail

Pelvic normal tissue contouring guidelines for radiation therapy: a Radiation Therapy Oncology Group consensus panel atlas.
MedLine Citation:
PMID:  22483697     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To define a male and female pelvic normal tissue contouring atlas for Radiation Therapy Oncology Group (RTOG) trials.
METHODS AND MATERIALS: One male pelvis computed tomography (CT) data set and one female pelvis CT data set were shared via the Image-Guided Therapy QA Center. A total of 16 radiation oncologists participated. The following organs at risk were contoured in both CT sets: anus, anorectum, rectum (gastrointestinal and genitourinary definitions), bowel NOS (not otherwise specified), small bowel, large bowel, and proximal femurs. The following were contoured in the male set only: bladder, prostate, seminal vesicles, and penile bulb. The following were contoured in the female set only: uterus, cervix, and ovaries. A computer program used the binomial distribution to generate 95% group consensus contours. These contours and definitions were then reviewed by the group and modified.
RESULTS: The panel achieved consensus definitions for pelvic normal tissue contouring in RTOG trials with these standardized names: Rectum, AnoRectum, SmallBowel, Colon, BowelBag, Bladder, UteroCervix, Adnexa_R, Adnexa_L, Prostate, SeminalVesc, PenileBulb, Femur_R, and Femur_L. Two additional normal structures whose purpose is to serve as targets in anal and rectal cancer were defined: AnoRectumSig and Mesorectum. Detailed target volume contouring guidelines and images are discussed.
CONCLUSIONS: Consensus guidelines for pelvic normal tissue contouring were reached and are available as a CT image atlas on the RTOG Web site. This will allow uniformity in defining normal tissues for clinical trials delivering pelvic radiation and will facilitate future normal tissue complication research.
Hiram A Gay; H Joseph Barthold; Elizabeth O'Meara; Walter R Bosch; Issam El Naqa; Rawan Al-Lozi; Seth A Rosenthal; Colleen Lawton; W Robert Lee; Howard Sandler; Anthony Zietman; Robert Myerson; Laura A Dawson; Christopher Willett; Lisa A Kachnic; Anuja Jhingran; Lorraine Portelance; Janice Ryu; William Small; David Gaffney; Akila N Viswanathan; Jeff M Michalski
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Publication Detail:
Type:  Consensus Development Conference; Journal Article; Practice Guideline; Research Support, N.I.H., Extramural     Date:  2012-04-06
Journal Detail:
Title:  International journal of radiation oncology, biology, physics     Volume:  83     ISSN:  1879-355X     ISO Abbreviation:  Int. J. Radiat. Oncol. Biol. Phys.     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-05-28     Completed Date:  2012-07-30     Revised Date:  2014-01-30    
Medline Journal Info:
Nlm Unique ID:  7603616     Medline TA:  Int J Radiat Oncol Biol Phys     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e353-62     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
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MeSH Terms
Adnexa Uteri
Femur / radiography
Intestines / radiography
Medical Illustration*
Organs at Risk / radiography*
Ovary / radiography
Pelvis / radiography*
Penis / radiography
Prostate / radiography
Radiation Oncology / standards*
Radiotherapy Planning, Computer-Assisted / methods,  standards*
Radiotherapy, Image-Guided / standards*
Sex Factors
Urinary Bladder / radiography
Grant Support
CA21661/CA/NCI NIH HHS; CA32115/CA/NCI NIH HHS; CA37422/CA/NCI NIH HHS; CA81647/CA/NCI NIH HHS; U10 CA021661-30/CA/NCI NIH HHS; U10 CA032115-26/CA/NCI NIH HHS; U10 CA037422-20/CA/NCI NIH HHS
Erratum In:
Int J Radiat Oncol Biol Phys. 2012 Sep 1;84(1):7

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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