Document Detail


Pelvic Ewing's sarcoma. Advances in treatment.
MedLine Citation:
PMID:  6863355     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In a study of eighteen patients with pelvic Ewing's sarcoma who were treated with a multidisciplinary approach, chemotherapy was effective in controlling systemic spread of the tumor. Surgery coupled with improved methods of chemotherapy provided results that were statistically superior to those obtained with radiation and chemotherapy alone in control of the local pelvic lesion. A twofold increase in the survival rate was seen at a median follow-up of thirty-six months in the patients who had the resection. Our results suggest that pelvic Ewing's sarcoma is best treated by initial chemotherapy, followed by local wide marginal resection of the pelvic lesion coupled with perimeter radiation therapy and concluded with additional chemotherapy. Survival rates of patients with pelvic Ewing's sarcoma may then approach the excellent survival rates of patients with lesions in more favorable anatomical locations.
Authors:
W K Li; J M Lane; G Rosen; R C Marcove; B Caparros; A Huvos; S Groshen
Related Documents :
20694075 - Trabectedin: the evidence for its place in therapy in the treatment of soft tissue sarc...
20872975 - Undifferentiated liver embryonal sarcoma in adults: a report of four cases and literatu...
15777885 - Extremity soft tissue sarcoma: controversial management issues.
22333995 - Location of aortic node metastases in locally advanced cervical cancer.
18308215 - Effect of neoadjuvant therapy on local recurrence after resection of pancreatic adenoca...
22241745 - Predicting survival in newly diagnosed idiopathic pulmonary fibrosis: a 3-year prospect...
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Journal of bone and joint surgery. American volume     Volume:  65     ISSN:  0021-9355     ISO Abbreviation:  J Bone Joint Surg Am     Publication Date:  1983 Jul 
Date Detail:
Created Date:  1983-08-26     Completed Date:  1983-08-26     Revised Date:  2010-10-25    
Medline Journal Info:
Nlm Unique ID:  0014030     Medline TA:  J Bone Joint Surg Am     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  738-47     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Antineoplastic Agents / therapeutic use
Child
Drug Therapy, Combination
Female
Humans
Male
Pelvic Neoplasms / drug therapy,  mortality,  surgery*
Sarcoma, Ewing's / drug therapy,  mortality,  surgery*
Grant Support
ID/Acronym/Agency:
DA-05826-18/DA/NIDA NIH HHS
Chemical
Reg. No./Substance:
0/Antineoplastic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Predicting the success of reambulation in patients with Duchenne muscular dystrophy.
Next Document:  Split posterior tibial-tendon transfer in spastic cerebral palsy.