Document Detail

Pelvic Ewing's sarcoma. Advances in treatment.
MedLine Citation:
PMID:  6863355     Owner:  NLM     Status:  MEDLINE    
In a study of eighteen patients with pelvic Ewing's sarcoma who were treated with a multidisciplinary approach, chemotherapy was effective in controlling systemic spread of the tumor. Surgery coupled with improved methods of chemotherapy provided results that were statistically superior to those obtained with radiation and chemotherapy alone in control of the local pelvic lesion. A twofold increase in the survival rate was seen at a median follow-up of thirty-six months in the patients who had the resection. Our results suggest that pelvic Ewing's sarcoma is best treated by initial chemotherapy, followed by local wide marginal resection of the pelvic lesion coupled with perimeter radiation therapy and concluded with additional chemotherapy. Survival rates of patients with pelvic Ewing's sarcoma may then approach the excellent survival rates of patients with lesions in more favorable anatomical locations.
W K Li; J M Lane; G Rosen; R C Marcove; B Caparros; A Huvos; S Groshen
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Journal of bone and joint surgery. American volume     Volume:  65     ISSN:  0021-9355     ISO Abbreviation:  J Bone Joint Surg Am     Publication Date:  1983 Jul 
Date Detail:
Created Date:  1983-08-26     Completed Date:  1983-08-26     Revised Date:  2010-10-25    
Medline Journal Info:
Nlm Unique ID:  0014030     Medline TA:  J Bone Joint Surg Am     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  738-47     Citation Subset:  AIM; IM    
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MeSH Terms
Antineoplastic Agents / therapeutic use
Drug Therapy, Combination
Pelvic Neoplasms / drug therapy,  mortality,  surgery*
Sarcoma, Ewing's / drug therapy,  mortality,  surgery*
Grant Support
Reg. No./Substance:
0/Antineoplastic Agents

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