Document Detail


Peginesatide: a potential erythropoiesis stimulating agent for the treatment of anemia of chronic renal failure.
MedLine Citation:
PMID:  21290916     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Erythropoiesis stimulating agents (ESAs) have revolutionized the management of anemia of chronic kidney disease (CKD). Peginesatide is an investigational pegylated, peptide-based, once-monthly ESA for increasing and maintaining hemoglobin (Hb). In phase 2 studies, peginesatide increases and maintains target Hb levels in patients with CKD, both those on hemodialysis and those not on hemodialysis; phase 3 trials have recently been completed. This article discusses unmet needs in the management of anemia of CKD, presents peginesatide attributes, reviews the results of select peginesatide clinical studies, and discusses the potential value of peginesatide as an alternative anemia management option.
Authors:
Sheila Doss; Brigitte Schiller
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Nephrology nursing journal : journal of the American Nephrology Nurses' Association     Volume:  37     ISSN:  1526-744X     ISO Abbreviation:  Nephrol Nurs J     Publication Date:    2010 Nov-Dec
Date Detail:
Created Date:  2011-02-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100909377     Medline TA:  Nephrol Nurs J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  617-26     Citation Subset:  N    
Affiliation:
Satellite Healthcare, Inc., San Jose, CA, USA. dosss@satellitehealth.com
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