| Pediatric perfusion MR imaging using arterial spin labeling. | |
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MedLine Citation:
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PMID: 16543090 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cerebral blood flow (CBF, cerebral perfusion) mirrors cerebral metabolic demand and neuronal function, and therefore, is a vital parameter in the evaluation of pediatric brain injury and recovery. Until recently, measurement of CBF involved intravenous bolus injection of contrast agents or nuclear medicine methods that were technically difficult or ethically problematic in pediatrics. The development of arterial spin label (ASL) perfusion MR imaging as a noninvasive method for measuring CBF allows for the increased ability to measure this vital physiologic parameter in any age group. This article presents the technical aspects of performing ASL perfusion MR imaging in pediatrics, and discusses its current use in clinical studies and its potential for influencing important management strategies in specific disease entities. |
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Authors:
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Jiongjiong Wang; Daniel J Licht |
Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Neuroimaging clinics of North America Volume: 16 ISSN: 1052-5149 ISO Abbreviation: Neuroimaging Clin. N. Am. Publication Date: 2006 Feb |
Date Detail:
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Created Date: 2006-03-17 Completed Date: 2006-05-18 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 9211377 Medline TA: Neuroimaging Clin N Am Country: United States |
Other Details:
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Languages: eng Pagination: 149-67, ix Citation Subset: IM |
Affiliation:
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Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA. wangj3@mail.med.upenn.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anemia, Sickle Cell
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complications,
physiopathology Brain Diseases / diagnosis*, etiology, physiopathology Cerebrovascular Circulation / physiology* Child Heart Defects, Congenital / complications, physiopathology* Humans Magnetic Resonance Angiography / methods* |
| Grant Support | |
ID/Acronym/Agency:
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HD049893/HD/NICHD NIH HHS; NS052380/NS/NINDS NIH HHS; R21 MH072576/MH/NIMH NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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