Document Detail

Pediatric penetrating keratoplasty in Shanghai: a retrospective multiple centre study from 2003 to 2007.
MedLine Citation:
PMID:  19080123     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: With advances in pediatric keratoplasty over the last two decades, the success rate of surgery has increased remarkably. However, few epidemiological studies in this field have been performed in China. The present study investigated the indications and characteristics of pediatric penetrating keratoplasty in Shanghai. METHODS: All records of pediatric keratoplasty performed on 156 eyes in 149 children (< 14 years) at four ophthalmic units in Shanghai during a 5-year period (2003 - 2007) were used for this retrospective study. Patients were from the Eye, Ear, Nose & Throat Hospital of Fudan University, Shanghai No.10 People's Hospital, Shanghai No.1 People's Hospital, and Shanghai Peace Ophthalmology Hospital; and included mostly school-age children (97 boys and 59 girls). RESULTS: The median age at surgery was 9 years with an interval quartile range of 6-12 years. Scarring after keratitis (29.5%, 46/156) and traumatic corneal scar (19.2%, 30/156) were the most common indications. Best Corrected Snellen visual acuity (BCSVA) was reported only in 72% (112/156) of cases. Visual acuity outcomes were significantly better for keratoplasty 1 year postoperatively compared to preoperative visual acuity (P = 0.001). Of all patients, 13% (14/112) achieved a BCSVA of 6/18 or better. None of the indications was associated with a higher rate of failure compared to after 1 year follow-up. CONCLUSION: We obtained valuable information on pediatric keratoplasty in Shanghai. There was no significant difference in graft survival rate among the two indications. Vision outcomes after corneal transplantation in Chinese children were significantly better compared with pre-operation status. In conclusion, corneal graft survival can be achieved in childhood.
Jia-xu Hong; Jian-jiang Xu; Min-jie Sheng; Yan Liu; Li Zhu
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Publication Detail:
Type:  Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Chinese medical journal     Volume:  121     ISSN:  0366-6999     ISO Abbreviation:  Chin. Med. J.     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-12-16     Completed Date:  2009-01-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7513795     Medline TA:  Chin Med J (Engl)     Country:  China    
Other Details:
Languages:  eng     Pagination:  1911-4     Citation Subset:  IM    
Department of Ophthalmology, Eye & Ear, Nose, Throat Hospital of Fudan University, Shanghai, China.
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MeSH Terms
Child, Preschool
Infant, Newborn
Keratoplasty, Penetrating*
Longitudinal Studies
Retrospective Studies
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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