Document Detail


Pediatric-onset Behçet disease in Bahrain: report of nine cases and literature review.
MedLine Citation:
PMID:  22827784     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: This report studies the clinical features of Behçet disease (BD) in children and compares our results with other international studies.
METHODS: We retrospectively reviewed patient data that included the clinical picture, HLA typing, and treatment in BD cases.
RESULTS: This study reviewed data from a total of nine children with BD. Median age at presentation was seven years, with a male to female ratio of 2:1. There was one patient who had Down's syndrome. Oral ulcers were present in all children, while genital ulcers were present in only 66% of cases. Skin manifestation was seen in 88% and uveitis in 55%. There was evidence of gastrointestinal (55%), neurological (55%), and musculoskeletal manifestations (77%). HLA B5 was positive in 66% of cases and 55% had positive family histories. Apart from gastrointestinal symptoms, our results were comparable with other studies.
CONCLUSION: Awareness of BD symptoms in the pediatric age group is crucial for early diagnosis and treatment. The coexistence of BD and Down's syndrome needs further genetic study, which may link these two major disorders.
Authors:
Zakiya Saleh Al Mosawi; Wafa Madan; Eman Fareed
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Archives of Iranian medicine     Volume:  15     ISSN:  1735-3947     ISO Abbreviation:  Arch Iran Med     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-07-25     Completed Date:  2012-11-13     Revised Date:  2013-05-15    
Medline Journal Info:
Nlm Unique ID:  100889644     Medline TA:  Arch Iran Med     Country:  Iran    
Other Details:
Languages:  eng     Pagination:  485-7     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Salmaniya Medical Complex, Kingdom of Bahrain. zakee08@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Bahrain
Behcet Syndrome / diagnosis*
Child
Female
Humans
Male
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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