Document Detail

Pediatric-onset Behçet disease in Bahrain: report of nine cases and literature review.
MedLine Citation:
PMID:  22827784     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: This report studies the clinical features of Behçet disease (BD) in children and compares our results with other international studies.
METHODS: We retrospectively reviewed patient data that included the clinical picture, HLA typing, and treatment in BD cases.
RESULTS: This study reviewed data from a total of nine children with BD. Median age at presentation was seven years, with a male to female ratio of 2:1. There was one patient who had Down's syndrome. Oral ulcers were present in all children, while genital ulcers were present in only 66% of cases. Skin manifestation was seen in 88% and uveitis in 55%. There was evidence of gastrointestinal (55%), neurological (55%), and musculoskeletal manifestations (77%). HLA B5 was positive in 66% of cases and 55% had positive family histories. Apart from gastrointestinal symptoms, our results were comparable with other studies.
CONCLUSION: Awareness of BD symptoms in the pediatric age group is crucial for early diagnosis and treatment. The coexistence of BD and Down's syndrome needs further genetic study, which may link these two major disorders.
Zakiya Saleh Al Mosawi; Wafa Madan; Eman Fareed
Related Documents :
7280234 - The ribs in thalassemia. ii. the pathogenesis of the changes.
22348744 - Cold-induced urticaria with a familial transmission: a case report and review of the li...
21224784 - Ejprm systematic continuous update on cochrane reviews in rehabilitation: news from the...
12405504 - Osteoid osteoma of the distal humerus mimicking tennis elbow.
6584824 - Endodontic recall radiographs: how reliable is our interpretation of endodontic success...
7230384 - Citrobacter diversus brain abscess and meningitis in neonates.
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Archives of Iranian medicine     Volume:  15     ISSN:  1735-3947     ISO Abbreviation:  Arch Iran Med     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-07-25     Completed Date:  2012-11-13     Revised Date:  2013-05-15    
Medline Journal Info:
Nlm Unique ID:  100889644     Medline TA:  Arch Iran Med     Country:  Iran    
Other Details:
Languages:  eng     Pagination:  485-7     Citation Subset:  IM    
Department of Pediatrics, Salmaniya Medical Complex, Kingdom of Bahrain.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Behcet Syndrome / diagnosis*
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Long-term continuous methimazole or radioiodine treatment for hyperthyroidism.
Next Document:  Robot-assisted thyroidectomy: early experience.