| Pediatric melioidosis in Pahang, Malaysia. | |
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MedLine Citation:
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PMID: 16211138 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Melioidosis is much less common in children than in adults. This study investigated the incidence, demographic characteristics, presenting symptoms and outcome of pediatric melioidosis in Pahang, Malaysia. This retrospective study included patients < or =18 years old with positive body fluid cultures for Burkholderia pseudomallei from January 2000 to June 2003. Data on culture results were obtained from 2 referral hospitals. The incidence of pediatric melioidosis was 0.68/100,000 population per year. Of the 13 patients identified during the study period, 10 were male; 9 were Malays, 2 were Indians and 2 were aborigines. The mean age of these patients was 9.5 +/- 5.4 years. None of the patients had a previous history of confirmed melioidosis or predisposing factors for infection. Localized melioidosis was the most common presentation (46.2%) followed by melioidosis with septic shock (38.4%). Among patients with localized melioidosis, head and neck involvement (83.3%) was the most common presentation (2 patients with cervical abscesses, 1 with submandibular abscesses and 2 with acute suppurative parotitis) and another patient had right axillary abscess. All of the patients with septic shock had pneumonia and 2 of them had multi-organ involvement. The mortality among patients with septic shock was 80% and death occurred within 24 h of admission in all cases. In contrast, no complications or death occurred among patients with localized melioidosis. Melioidosis with septic shock is less common than localized melioidosis in pediatric patients, but is associated with very high mortality. |
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Authors:
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Hin-Soon How; Kok-Huan Ng; Heng-Bon Yeo; Hoi-Poh Tee; Anis Shah |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi Volume: 38 ISSN: 1684-1182 ISO Abbreviation: J Microbiol Immunol Infect Publication Date: 2005 Oct |
Date Detail:
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Created Date: 2005-10-07 Completed Date: 2005-12-08 Revised Date: 2007-06-21 |
Medline Journal Info:
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Nlm Unique ID: 100956211 Medline TA: J Microbiol Immunol Infect Country: China (Republic : 1949- ) |
Other Details:
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Languages: eng Pagination: 314-9 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine, Kulliyyah of Medicine, International Islamic University Malaysia, Pahang, Malaysia. how_sh@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abscess Anti-Bacterial Agents / pharmacology, therapeutic use Body Fluids / microbiology Burkholderia pseudomallei / drug effects, isolation & purification* Child Child, Preschool Female Humans Incidence Malaysia / epidemiology Male Melioidosis* / complications, drug therapy, epidemiology Microbial Sensitivity Tests Parotitis Retrospective Studies Shock, Septic / mortality |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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