| Pediatric cervical chordoma: report of two cases and a review of the current literature. | |
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MedLine Citation:
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PMID: 20094721 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: The majority of chordomas occur between the fifth and seventh decades of life and are thus extremely rare in children, which account for less than 5% of all spinal chordoma cases. CASE REPORT: We report on the development of this rare condition in two boys aged 7 and 10 years. One patient presented with a palpable neck mass and dysphagia, while the other presented with posterior neck pain. Radiological studies revealed an extensive mass in the cervical vertebrae and paravertebral soft tissue of both patients. The tumors were subtotally removed in an attempt to improve the success of adjuvant proton beam radiotherapy. Pathological examination, which included immunohistochemical staining, revealed chordoma of the cervical spine in both patients. CONCLUSION: Although en bloc resection is the ideal modality for treatment of chordoma, such a procedure is often associated with a significant risk of surgical morbidity due to the tumor location. Therefore, piecemeal resection followed by postoperative adjuvant radiotherapy, including proton radiotherapy or radiosurgery, should be considered in such cases. |
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Authors:
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Gwi Hyun Choi; Moon-Sool Yang; Do Heum Yoon; Hyun Chyul Shin; Keung Nyun Kim; Seong Yi; Dong Yeop Lee; Poong Gi Ahn; Yoon Ha |
Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review Date: 2010-01-22 |
Journal Detail:
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Title: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery Volume: 26 ISSN: 1433-0350 ISO Abbreviation: Childs Nerv Syst Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-05-12 Completed Date: 2010-08-31 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8503227 Medline TA: Childs Nerv Syst Country: Germany |
Other Details:
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Languages: eng Pagination: 835-40 Citation Subset: IM |
Affiliation:
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Department of Neurosurgery, Spine and Spinal Cord Institute, College of Medicine, Yonsei University, 134 Shinchon-dong, Seodaemun-gu, Seoul, 120-752, Republic of Korea. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cervical Vertebrae Child Chordoma / pathology, radiotherapy*, surgery* Combined Modality Therapy / methods Follow-Up Studies Humans Immunohistochemistry Magnetic Resonance Imaging Male Neurosurgical Procedures / methods Protons / therapeutic use Spinal Cord / metabolism, radiography, surgery Spinal Cord Neoplasms / pathology, radiotherapy*, surgery* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Protons |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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