Document Detail

Pediatric cancer pain management at a regional cancer center: implementation of WHO Analgesic Ladder.
MedLine Citation:
PMID:  19583072     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To collect data on the prevalence of various types of cancer pain in a sample of children with cancer, and to implement the WHO Analgesic Ladder in the management of pain in pediatric cancer.
METHODS: Eighty four pediatric patients suffering of cancer pain were studied during the period 2001-2006. Patients were requested to rate their global intensity of pain on 0-100 mm visual analogue scale (VAS 0 = no pain, 100 = maximum pain). Pain management was performed in accordance with the WHO Analgesic Ladder for cancer pain. Patients were followed up weekly for three weeks.
RESULTS: Of the 84 pediatric children with cancer, pain was nociceptive in 26 (31%), neuropathic in 12 (14.3%) and mixed in 46 (54.8%). Almost 7 (8.3%) of patients were on WHO step 3 at baseline. Thereafter the WHO step 3 increased; first week visit 36 (43%) patients; second week visit 58 (69%), and third week 69 (82.1%). At baseline, 40 (47.6%) patients took NSAID only, 2 (2.4%) patients took adjuvant, while 38 (45.2 %) patients took combination of NSAID and adjuvant treatment. There was statistically significant (p = 0.000) reduction in VAS as time progressed.
CONCLUSION: Cancer pain in pediatric age group can be well managed in accordance with the WHO Analgesic Ladder. Aggressive symptoms and control of treatment of related side effect are also needed to ensure successful implementation and the WHO Analgesic Ladder.
Seema Mishra; Sushma Bhatnagar; Manisha Singh; Deepak Gupta; Roopesh Jain; Himanshu Chauhan; Gaurav Nirwani Goyal
Publication Detail:
Type:  Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Middle East journal of anaesthesiology     Volume:  20     ISSN:  0544-0440     ISO Abbreviation:  Middle East J Anaesthesiol     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-07-08     Completed Date:  2009-08-04     Revised Date:  2014-10-10    
Medline Journal Info:
Nlm Unique ID:  8604187     Medline TA:  Middle East J Anaesthesiol     Country:  Lebanon    
Other Details:
Languages:  eng     Pagination:  239-44     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Analgesics / therapeutic use*
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
Cancer Care Facilities
Child, Preschool
Follow-Up Studies
Neoplasms / physiopathology*
Pain / drug therapy*,  etiology
Pain Measurement
Practice Guidelines as Topic
Prospective Studies
Time Factors
Treatment Outcome
World Health Organization
Reg. No./Substance:
0/Analgesics; 0/Anti-Inflammatory Agents, Non-Steroidal

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Attenuation of hemodynamic responses following laryngoscopy and tracheal intubation -- comparative a...
Next Document:  The prophylactic effect of rectal acetaminophen on postoperative pain and opioid requirements after ...