| Pediatric vasculitides: a generalists approach. | |
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MedLine Citation:
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PMID: 20803178 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Vasculitis is defined as the presence of inflammation in a blood vessel that may occur as a primary process or secondary to an underlying disease. Primary vasculitides are rare in children. These are defined by both the size of vessels involved and the type of inflammatory response. Clinical features consist of multi-organ involvement on a background of constitutional features reflecting the size and location of the blood vessels involved. Whilst some vasculitides are best diagnosed clinically, many forms require sophisticated imaging and other investigations (auto antibodies) to reveal the correct diagnosis. Prompt recognition and treatment is crucial as many of the vasculitides cause significant morbidity or mortality. Treatment options range from symptomatic therapy, immunosuppresive agents, intravenous immunoglobulin (IVIG) or biologic agents and are determined by the type of vasculitis, the severity of the inflammation, and the organ systems affected. Early detection and aggressive treatment is crucial for the best outcomes in the most severe forms of childhood vasculitis. |
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Authors:
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Raju P Khubchandani; V Viswanathan |
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Publication Detail:
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Type: Journal Article Date: 2010-08-28 |
Journal Detail:
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Title: Indian journal of pediatrics Volume: 77 ISSN: 0973-7693 ISO Abbreviation: Indian J Pediatr Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-10-27 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0417442 Medline TA: Indian J Pediatr Country: India |
Other Details:
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Languages: eng Pagination: 1165-71 Citation Subset: IM |
Affiliation:
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Pediatric Rheumatology Clinic, Department of Pediatrics, Jaslok Hospital and Research Centre, Nana Chowk, Mumbai, 400007, India. rajukhubchandani@yahoo.co.in |
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