Document Detail

Paediatric Hashimoto encephalopathy, refractory epilepsy and immunoglobulin treatment - unusual case report and review of the literature.
MedLine Citation:
PMID:  20678162     Owner:  NLM     Status:  MEDLINE    
BACKGROUND:  Hashimoto encephalopathy (HE) is a rare autoimmune disorder. It is defined as a 'corticosteroid-responsive encephalopathy associated with thyroiditis'.
CLINICAL OBSERVATION:   We describe a boy who suffered from HE, responded only to intravenous immunoglobulin therapy. This is the first case report of immunoglobulin therapy in paediatric HE.
CONCLUSION:  After review of the literature, we recommend that unexplained encephalopathy in children should lead to evaluation of thyroid autoantibody titres. Immunoglobulins should be considered.
I Berger; Y Castiel; T Dor
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  99     ISSN:  1651-2227     ISO Abbreviation:  Acta Paediatr.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-02     Completed Date:  2011-01-20     Revised Date:  2012-09-10    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  1903-5     Citation Subset:  IM    
Copyright Information:
© 2010 The Author(s)/Journal Compilation © 2010 Foundation Acta Paediatrica.
The Neuro-Pediatric Unit, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
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MeSH Terms
Encephalitis / complications,  therapy*
Epilepsy / etiology
Hashimoto Disease / complications,  therapy*
Immunization, Passive*
Immunoglobulins, Intravenous
Treatment Outcome
Reg. No./Substance:
0/Immunoglobulins, Intravenous
Comment In:
Acta Paediatr. 2011 Jan;100(1):5; discussion 5-6   [PMID:  20880150 ]

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