| Peanut protein as a major cause of adverse food reactions in patients with atopic dermatitis. | |
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MedLine Citation:
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PMID: 2792753 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Peanuts, along with milk and eggs, have been documented to account for approximately 80% of adverse reactions to foods in patients with atopic dermatitis. Over the past 3 years, we have evaluated 71 patients with atopic dermatitis, ranging from mild to severe in nature. These patients were initially evaluated by allergy prick skin testing and when appropriate had double-blind placebo-controlled food challenges done. Thirty-nine (55%) patients had a positive prick skin test to one of the foods tested. There were 80 food challenges performed with peanut, accounting for 12 (32%) of the 38 positive challenges in 23 (31%) patients. As in earlier studies, patients developed skin (97%), respiratory (55%), and gastrointestinal (32%) symptoms during the challenge. Of the five patients with histories of prior anaphylactic reactions four (80%) were to peanut. These studies indicate that children with all degrees of atopic dermatitis may benefit from evaluation for food hypersensitivity. They also show that peanut is a major food protein responsible for these reactions. |
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Authors:
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A W Burks; L W Williams; S B Mallory; M A Shirrell; C Williams |
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Publication Detail:
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Type: Clinical Trial; Controlled Clinical Trial; Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Allergy proceedings : the official journal of regional and state allergy societies Volume: 10 ISSN: 1046-9354 ISO Abbreviation: Allergy Proc Publication Date: 1989 Jul-Aug |
Date Detail:
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Created Date: 1989-11-21 Completed Date: 1989-11-21 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8902396 Medline TA: Allergy Proc Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 265-9 Citation Subset: IM |
Affiliation:
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Department of Pediatrics and Dermatology, University of Arkansas for Medical Sciences, Little Rock. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Animals Arachis hypogaea / adverse effects* Chickens Dermatitis, Atopic / immunology* Dietary Proteins / adverse effects Double-Blind Method Eggs Female Fishes Food Hypersensitivity / immunology* Humans Male Meat / analysis Milk / immunology Plant Proteins / adverse effects* Skin Tests |
| Grant Support | |
ID/Acronym/Agency:
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AI26629/AI/NIAID NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Dietary Proteins; 0/Plant Proteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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