Document Detail


Peanut protein as a major cause of adverse food reactions in patients with atopic dermatitis.
MedLine Citation:
PMID:  2792753     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Peanuts, along with milk and eggs, have been documented to account for approximately 80% of adverse reactions to foods in patients with atopic dermatitis. Over the past 3 years, we have evaluated 71 patients with atopic dermatitis, ranging from mild to severe in nature. These patients were initially evaluated by allergy prick skin testing and when appropriate had double-blind placebo-controlled food challenges done. Thirty-nine (55%) patients had a positive prick skin test to one of the foods tested. There were 80 food challenges performed with peanut, accounting for 12 (32%) of the 38 positive challenges in 23 (31%) patients. As in earlier studies, patients developed skin (97%), respiratory (55%), and gastrointestinal (32%) symptoms during the challenge. Of the five patients with histories of prior anaphylactic reactions four (80%) were to peanut. These studies indicate that children with all degrees of atopic dermatitis may benefit from evaluation for food hypersensitivity. They also show that peanut is a major food protein responsible for these reactions.
Authors:
A W Burks; L W Williams; S B Mallory; M A Shirrell; C Williams
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Allergy proceedings : the official journal of regional and state allergy societies     Volume:  10     ISSN:  1046-9354     ISO Abbreviation:  Allergy Proc     Publication Date:    1989 Jul-Aug
Date Detail:
Created Date:  1989-11-21     Completed Date:  1989-11-21     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8902396     Medline TA:  Allergy Proc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  265-9     Citation Subset:  IM    
Affiliation:
Department of Pediatrics and Dermatology, University of Arkansas for Medical Sciences, Little Rock.
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MeSH Terms
Descriptor/Qualifier:
Adult
Animals
Arachis hypogaea / adverse effects*
Chickens
Dermatitis, Atopic / immunology*
Dietary Proteins / adverse effects
Double-Blind Method
Eggs
Female
Fishes
Food Hypersensitivity / immunology*
Humans
Male
Meat / analysis
Milk / immunology
Plant Proteins / adverse effects*
Skin Tests
Grant Support
ID/Acronym/Agency:
AI26629/AI/NIAID NIH HHS
Chemical
Reg. No./Substance:
0/Dietary Proteins; 0/Plant Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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