| Peanut allergy and anaphylaxis. | |
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MedLine Citation:
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PMID: 21051210 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Peanuts are a frequent cause of food allergy and the most common cause of fatal food-induced anaphylaxis in the U.S. Advances during the past two years have promoted our understanding of peanut allergens and peanut allergy prevalence, etiology, diagnosis, and therapy. The advances highlighted in this review include evidence that the peanut allergens most important in disease differ in different parts of the world, that early oral exposure to peanuts may decrease the frequency of peanut allergy, while early nonoral exposure may have the opposite effect, that complement activation by peanut constituents appears to promote peanut-induced anaphylaxis and that oral immunotherapy, anti-IgE antibody, and a herbal formulation are promising approaches for the treatment of this disorder. |
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Authors:
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Fred D Finkelman |
Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review Date: 2010-11-02 |
Journal Detail:
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Title: Current opinion in immunology Volume: 22 ISSN: 1879-0372 ISO Abbreviation: Curr. Opin. Immunol. Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-12-06 Completed Date: 2011-03-25 Revised Date: 2013-05-27 |
Medline Journal Info:
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Nlm Unique ID: 8900118 Medline TA: Curr Opin Immunol Country: England |
Other Details:
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Languages: eng Pagination: 783-8 Citation Subset: IM |
Copyright Information:
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Copyright © 2010. Published by Elsevier Ltd. |
Affiliation:
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Department of Medicine, Cincinnati Veterans Affairs Medical Center, Cincinnati, OH 45220, United States. ffinkelman@pol.net |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anaphylaxis
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immunology* Animals Humans Peanut Hypersensitivity / immunology* |
| Grant Support | |
ID/Acronym/Agency:
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R21 AI079947/AI/NIAID NIH HHS; R21 AI079947-01/AI/NIAID NIH HHS; R21 AI079947-02/AI/NIAID NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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