Document Detail

Peanut allergy and anaphylaxis.
MedLine Citation:
PMID:  21051210     Owner:  NLM     Status:  MEDLINE    
Peanuts are a frequent cause of food allergy and the most common cause of fatal food-induced anaphylaxis in the U.S. Advances during the past two years have promoted our understanding of peanut allergens and peanut allergy prevalence, etiology, diagnosis, and therapy. The advances highlighted in this review include evidence that the peanut allergens most important in disease differ in different parts of the world, that early oral exposure to peanuts may decrease the frequency of peanut allergy, while early nonoral exposure may have the opposite effect, that complement activation by peanut constituents appears to promote peanut-induced anaphylaxis and that oral immunotherapy, anti-IgE antibody, and a herbal formulation are promising approaches for the treatment of this disorder.
Fred D Finkelman
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review     Date:  2010-11-02
Journal Detail:
Title:  Current opinion in immunology     Volume:  22     ISSN:  1879-0372     ISO Abbreviation:  Curr. Opin. Immunol.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-12-06     Completed Date:  2011-03-25     Revised Date:  2014-09-21    
Medline Journal Info:
Nlm Unique ID:  8900118     Medline TA:  Curr Opin Immunol     Country:  England    
Other Details:
Languages:  eng     Pagination:  783-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2010. Published by Elsevier Ltd.
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MeSH Terms
Anaphylaxis / immunology*
Peanut Hypersensitivity / immunology*
Grant Support
R21 AI079947/AI/NIAID NIH HHS; R21 AI079947/AI/NIAID NIH HHS; R21 AI079947-01/AI/NIAID NIH HHS; R21 AI079947-02/AI/NIAID NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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