Document Detail

Peak systolic stress-rate-corrected mean velocity of fiber shortening in preterm and fullterm infants.
MedLine Citation:
PMID:  9607394     Owner:  NLM     Status:  MEDLINE    
The relation of rate-corrected mean velocity of fiber shortening (mVcfc)-end-systolic wall stress (ESS) is a load-independent index of left ventricular contractility, but involves simultaneous M-mode echocardiography, carotid or axillary pulse tracing and blood pressure determination, which may be impractical in younger infants. We examined whether the relation of the peak systolic wall stress (PSS)-mVcfc could be used as a simpler method of assessing left ventricular contractility in preterm and fullterm infants. In 45 preterm and fullterm infants, mVcfc, ESS, and PSS were determined using echocardiography, axillary pulse tracing and blood pressure measurement. Five patients with left ventricular dysfunction or low cardiac output state were also studied. The relation of PSS and ESS was PSS=5.19+1.04 ESS (r=0.98, p<0.01). The slope of mVcfc=1.58-0.012 ESS (r=-0.78, p<0.01) was nearly identical to that of mVcfc=1.60-0.011 PSS (r=-0.75, p<0.01), with no difference in the regression coefficients. The relationship of PSS and ESS in 5 patients was very close and the slope of the regression line was nearly identical to that of 45 infants. The relation of mVcfc PSS correlates well with the relation using ESS and can be used as a simple method of assessing left ventricular contractility.
K Harada; Y Takahashi; M Toyono; T Orino; G Takada
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Tohoku journal of experimental medicine     Volume:  184     ISSN:  0040-8727     ISO Abbreviation:  Tohoku J. Exp. Med.     Publication Date:  1998 Jan 
Date Detail:
Created Date:  1998-07-27     Completed Date:  1998-07-27     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0417355     Medline TA:  Tohoku J Exp Med     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  13-20     Citation Subset:  IM    
Department of Pediatrics, Akita University School of Medicine, Japan.
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MeSH Terms
Blood Pressure / physiology
Cardiac Output, Low / physiopathology
Infant, Newborn / physiology*
Infant, Premature / physiology*
Muscle Fibers, Skeletal / physiology
Myocardial Contraction / physiology*
Stress, Mechanical
Time Factors
Ventricular Dysfunction, Left / physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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