Document Detail


Peak expiratory flow in symptomless elderly smokers and ex-smokers.
MedLine Citation:
PMID:  2497893     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Values of peak expiratory flow (PEF) in 142 current smokers (116 men, 26 women) and 108 ex-smokers (88 men, 20 women) aged 55 or over were compared with the predicted values obtained in lifelong nonsmokers of the same age range. None of the subjects had been liable during childhood or subsequently to expectoration, lower respiratory tract infection, wheeze, or shortness of breath. Observed values of PEF were expressed as differences from predicted. Analysis of the relation between smoking state and ventilatory function in the men disclosed significant reductions of PEF in current smokers, the deficits increasing with the amount smoked from a mean of 48.1 l/min in those smoking fewer than 20 cigarettes a day to 73.3 l/min in smokers of 20 or more a day. Significant reductions of PEF were also found in women who were currently smoking (mean 47.4 l/min) and in male ex-smokers of 20 or more cigarettes a day (mean 27.8 l/min). There was no significant reduction of PEF in male or female ex-smokers of fewer than 20 cigarettes a day. These findings suggest that factors besides smoking are concerned in the development of irreversible airflow obstruction.
Authors:
I Gregg; A J Nunn
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  BMJ (Clinical research ed.)     Volume:  298     ISSN:  0959-8138     ISO Abbreviation:  BMJ     Publication Date:  1989 Apr 
Date Detail:
Created Date:  1989-07-07     Completed Date:  1989-07-07     Revised Date:  2012-05-09    
Medline Journal Info:
Nlm Unique ID:  8900488     Medline TA:  BMJ     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1071-2     Citation Subset:  AIM; IM    
Affiliation:
Faculty of Medicine, University of Southampton.
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MeSH Terms
Descriptor/Qualifier:
Aged
Airway Obstruction / physiopathology
Female
Humans
Lung / physiopathology*
Male
Middle Aged
Peak Expiratory Flow Rate
Regression Analysis
Sex Factors
Smoking / physiopathology*
Comments/Corrections

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