Document Detail


Peak expiratory flow as a screening tool to detect airflow obstruction in a primary health care setting.
MedLine Citation:
PMID:  22409956     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Peak expiratory flow (PEF) measurement is less expensive and requires fewer skills than spirometry testing. It is thus expected to be a reasonable substitute for spirometry in airflow obstruction screening when spirometry is unavailable.OBJECTIVES: To evaluate the validation of PEF measurement in the detection of airflow obstruction using newly established regression equations.METHODS: The PEFs of 553 'normal' participants aged 40-85 years were measured using mechanical devices. Based on these data, regression equations were generated to predict normal PEF values. Data were then collected from 3379 subjects. The specificity and sensitivity of the different predicted PEF cut-off points for detecting airflow obstruction were evaluated by spirometry, based on previously generated regression equations.RESULTS: Using newly established reference values for PEF, PEF had higher sensitivity and specificity than the questionnaire in detection of airflow obstruction. That PEF < 80% of predicted was more effective in the detection of airflow obstruction was confirmed by the lower limit of normal of forced expiratory volume in 1 second/forced vital capacity, Global Initiative for Chronic Obstructive Lung Disease (GOLD), and GOLD plus symptom, with a sensitivity of 78.7%, 76.8%, 85.3% and a specificity of 81.9%, 83.8%, 81.4%, respectively.CONCLUSIONS: Mechanical PEF may be a reasonable method of screening for airflow obstruction in settings where spirometry is unavailable.
Authors:
J Tian; Y Zhou; J Cui; D Wang; X Wang; G Hu; Y Tian; Y Jiang; J Zheng; J Wang; N Zhong; P Ran
Related Documents :
15938656 - Mixing realities? an application of augmented reality for the treatment of cockroach ph...
16862446 - Decision models in the evaluation of psychotropic drugs : useful tool or useless toy?
19908926 - Bayesian modelling of healthcare resource use in multinational randomized clinical trials.
18222556 - Modelling geographic variation in the cost-effectiveness of control policies for infect...
10602146 - Exploring spatial patterns of mortality: the new atlas of united states mortality.
19955326 - Analysis of censored exposure data by constrained maximization of the shapiro-wilk w st...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-3-7
Journal Detail:
Title:  The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease     Volume:  -     ISSN:  1815-7920     ISO Abbreviation:  -     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-3-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9706389     Medline TA:  Int J Tuberc Lung Dis     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Lung function in children and adolescents with juvenile idiopathic arthritis during long-term treatm...
Next Document:  Psychiatric disorders and aggression in the printed media: is there a link? A central European persp...