| Peak Skin and Eye Lens Radiation Dose From Brain Perfusion CT Based on Monte Carlo Simulation. | |
| | |
MedLine Citation:
|
PMID: 22268186 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
OBJECTIVE: The purpose of our study was to accurately estimate the radiation dose to skin and the eye lens from clinical CT brain perfusion studies, investigate how well scanner output (expressed as volume CT dose index [CTDI(vol)]) matches these estimated doses, and investigate the efficacy of eye lens dose reduction techniques. MATERIALS AND METHODS: Peak skin dose and eye lens dose were estimated using Monte Carlo simulation methods on a voxelized patient model and 64-MDCT scanners from four major manufacturers. A range of clinical protocols was evaluated. CTDI(vol) for each scanner was obtained from the scanner console. Dose reduction to the eye lens was evaluated for various gantry tilt angles as well as scan locations. RESULTS: Peak skin dose and eye lens dose ranged from 81 mGy to 348 mGy, depending on the scanner and protocol used. Peak skin dose and eye lens dose were observed to be 66-79% and 59-63%, respectively, of the CTDI(vol) values reported by the scanners. The eye lens dose was significantly reduced when the eye lenses were not directly irradiated. CONCLUSION: CTDI(vol) should not be interpreted as patient dose; this study has shown it to overestimate dose to the skin or eye lens. These results may be used to provide more accurate estimates of actual dose to ensure that protocols are operated safely below thresholds. Tilting the gantry or moving the scanning region further away from the eyes are effective for reducing lens dose in clinical practice. These actions should be considered when they are consistent with the clinical task and patient anatomy. |
| | |
Authors:
|
Di Zhang; Chris H Cagnon; J Pablo Villablanca; Cynthia H McCollough; Dianna D Cody; Donna M Stevens; Maria Zankl; John J Demarco; Adam C Turner; Maryam Khatonabadi; Michael F McNitt-Gray |
Related Documents
:
|
19391106 - Chromosomal mobilization and reintegration of sleeping beauty and piggybac transposons. 19134176 - Sleeping to fuel the immune system: mammalian sleep and resistance to parasites. 3156646 - Influence of some agents that affect 5-hydroxytryptamine metabolism and receptors on ni... 6358486 - Sleep without drugs. 15559646 - Foldable acrylic versus rigid polymethylmethacrylate intraocular lens in combined phaco... 16987226 - Inducible and neuronal nitric oxide synthases (nos) have complementary roles in recover... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: AJR. American journal of roentgenology Volume: 198 ISSN: 1546-3141 ISO Abbreviation: AJR Am J Roentgenol Publication Date: 2012 Feb |
Date Detail:
|
Created Date: 2012-01-23 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7708173 Medline TA: AJR Am J Roentgenol Country: United States |
Other Details:
|
Languages: eng Pagination: 412-7 Citation Subset: AIM; IM |
Affiliation:
|
Department of Radiological Sciences, UCLA David Geffen School of Medicine, Los Angeles, CA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Noise Reduction to Decrease Radiation Dose and Improve Conspicuity of Hepatic Lesions at Contrast-En...
Next Document: MRI appearance of the proximal hamstring tendons in patients with and without symptomatic proximal h...